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系統識別號 U0026-3108201012570300
論文名稱(中文) 神經回饋訓練在正常人自主神經活性與認知功能之探討
論文名稱(英文) Neurofeedback training on sympathovagal activity and cognitive function in humans
校院名稱 成功大學
系所名稱(中) 認知科學研究所
系所名稱(英) Institute of Cognitive Science
學年度 98
學期 2
出版年 99
研究生(中文) 陳慈姍
研究生(英文) Tzu-Shan Chen
學號 u7697105
學位類別 碩士
語文別 中文
論文頁數 65頁
口試委員 指導教授-蕭富仁
口試委員-謝淑蘭
口試委員-廖敏如
中文關鍵字 神經回饋  自律神經系統  Mu rhythm  SMR  自主神經活性  認知功能 
英文關鍵字 neurofeedback  mu rhythm  SMR  sympathovagal  cognitive function 
學科別分類
中文摘要 神經回饋為一種利用腦電波來進行的操作型制約學習,許多研究報告證實神經回饋可以有效地改善癲癇、注意力缺失過動疾患與過度焦慮或憂鬱等症狀,或可以增進認知功能。目前文獻中神經回饋多採用sensorimotor rhythm (SMR, 12-15 Hz)做為臨床上治療之回饋腦電波訊號,但是SMR腦部訊號的訓練與認知功能的改變卻仍存在著爭議,而且神經回饋訓練與最後症狀改善的關係仍然不清楚,因此新的神經回饋訓練絕對是需要被驗證開發。本論文比較正常人身上對於不同的腦訊號回饋(隨機回饋、SMR、mu rhythm (8-12 Hz))訓練對於認知功能與自主神經活性的影響,在四個星期共12次四十分鐘的訓練之後,本實驗首度證實不管是mu rhythm組的mu rhythm或SMR組的SMR能量均有顯著的上升,而且mu rhythm組在副交感神經活性與記憶方面均有顯著增進的表現,此增進能力皆與mu rhythm增加的次數或能量呈現顯著正相關。因此,本研究結果支持mu rhythm之神經回饋訓練有助於記憶功能增進以及放鬆相關之副交感活性加強。
英文摘要 Neurofeedback (NFT), an operant conditioning through electroencephagram (EEG) feedback training, has been reported to not only be an effective therapy of epilepsy, attention deficit hyperactivity disorders (ADHD), anxiety, and depression, but also improve cognitive function. A great number of studies have used sensorimotor rhythm (SMR, 12-15 Hz) as feedback activity of a NFT to widely apply in clinic. However, benefit of SMR training on cognitive function is still controversial. The relationship between the SMR training and functional outcome is also inconclusive. To further clarify the effect of NFT, three feedback signals (random frequency, SMR, and mu rhythm (8-12 Hz)) were evaluated in normal participants in terms of three memory tasks and sympathovagal indexes derived from heart rate variability. Each training session was 0.5 hour three times per week lasting for four weeks. A significantly elevated trend was found in powers of either SMR or mu rhythm during a NFT. A significant enhancement on memory performance and vagal activity only was found in the group of mu-rhythm NFT. Enhancement of these two outcomes showed a significantly positive relationship with increased number or total power of mu rhythm. Our results suggest that the mu-rhythm NFT has a great benefit on memory facilitation and very helpful for eliciting the relaxation-related vagal activity.
論文目次 目錄
摘要 I
Abstract II
致謝 III
表目錄 VII
圖目錄 VIII
符號 X
Chapter1 緒論 1
1.1 神經回饋的歷史與發展 1
1.2 目的與假設 4
Chapter2 研究方法 5
2.1 受試者 5
2.2 實驗儀器 5
2.2.1 腦部與生理訊號 5
2.2.2 認知行為測驗 6
2.3 實驗方法 6
2.3.1 腦波訊號 (electroencephalograph, EEG) 6
2.3.2 生理訊號(electrocardiography, ECG) 7
2.4 實驗材料 7
2.41 問卷評估 7
2.42 認知行為能力評估 12
2.5 實驗流程 14
2.6 分析方法 16
2.61 腦波訊號 16
2.62 心率變異分析 (Heart rate variability, HRV) 17
2.63 認知能力作業分析 18
2.64 問卷分析 18
Chapter3 結果 18
3.1 問卷分析結果 18
3.2 腦波訊號分析結果 20
3.3 心率變異分析結果 23
3.4 認知作業分析結果 26
Chapter4 討論 28
4.1 結果討論 28
4.2 結論 30
Chapter5 未來工作 31
參考文獻 32

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