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系統識別號 U0026-3105201712450700
論文名稱(中文) 矯正齒移動分析-立體影像追蹤
論文名稱(英文) Movement analysis of orthodontic toothstereovision tracking
校院名稱 成功大學
系所名稱(中) 生物醫學工程學系
系所名稱(英) Department of BioMedical Engineering
學年度 105
學期 1
出版年 105
研究生(中文) 曾浩垣
研究生(英文) Hao-Yuan Tseng
學號 P86021045
學位類別 碩士
語文別 中文
論文頁數 51頁
口試委員 指導教授-張志涵
口試委員-胡晉嘉
口試委員-莊淑芬
口試委員-劉佳觀
中文關鍵字 矯正齒移動  矯正力  立體影像 
英文關鍵字 stereovision  orthodontic tooth movement  orthodontic force 
學科別分類
中文摘要 矯正牙齒在臨床治療上已有很高的成功率,但是對於矯正齒的移動仍然無法提供一個良好的記錄方式。近年來牙齒移動的研究都侷限於石膏模型數位化量測或是錐狀射束電腦斷層掃描(CBCT)重建,然而這些方法在臨床追蹤上仍然有許多限制。因此本研究目的是依據先前實驗室的研究結果,利用立體影像系統來取得牙齒在空間中三維的資訊,追蹤其移動過程。藉由觀察一名受試者,進一步分析矯正齒平移及旋轉的方式;並利用六軸荷重元量測施加的矯正力,評估矯正力與矯正齒位移的關係。本研究使用兩台數位相機建立立體影像追蹤系統,並建立矯正器座標系於矯正器上,及牙齒坐標系於抵抗中心上(center of resistance),用於分析牙齒位移的改變量;另外,使用數位口掃模型、Solidworks和3D-printing設計和製造荷重元的夾具,用於量測矯正力。實驗結果顯示立體影像系統精確度評估最大誤差小於2%,並且誤差來自於影像的清晰度。測量實驗結果顯示,由矯正器座標系來看前門齒,追蹤58天後總位移量為0.94mm,有一半的位移發生於第一天,並伴隨遠心往近心的Angulation及近心側,舌側往唇側順時鐘的Rotation。由牙齒座標系來看前門齒,追蹤58天後可以觀察總位移量為0.92 mm,但是在矯正初期有0.7mm大位移產生,並且伴隨者舌側往唇側的Torque。以定性的角度看,追蹤牙齒的角度變化量與臨床醫師判斷的結果是一致的,並且明顯的觀察到牙齒三個時期的移動趨勢(Initial phase、Lag phase、Postlag phase)。以定量的角度來看,矯正器座標系與牙齒坐標系角度變化量有相同的結果,顯示透過觀察矯正器角度改變量,同時可以用於描述牙根的角度改變量。但是在實驗初期牙齒座標系的位移量,與先前研究牙周韌帶最大變形量的結果相比,部分追蹤點的位移量有較大的誤差。本實驗成功的利用重疊矯正器座標系原點,量測角度變化量,並結合矯正器位移量,提供了一個用於描述矯正牙齒的移動過程的方法。
英文摘要 SUMMARY
The aim of this study is to track tooth movement under orthodontic treatment based on stereovision approach and combine with 3D scanning as well as 3D printing for orthodontic force measurement. The stereovision system tracks the movement of the orthodontic tooth by employing laser-markered brackets. This system consisted of two cameras with their relative positions calibrated. The measured movements were registered in the bracket coordinate system. Both translation and rotation were evaluated. Moreover, artificial model, from 3D printing, of the orthodontic system was established and integrated with six-axis load cell to measure the orthodontic force. The results showed that, qualitatively, the measured tooth movement was consistent with the clinical report (Kaare et al. 1969), that is a three-stage movements as the treatment progress. Quantitatively, the rotations, in addition to translation, could be identified directly from the follow up in clinical suitation. And the 3D model integrated with a six-axis load cell system provides a practical method to measure the orthodontic force in vitro, qualitatively validated by the measured tooth movement from stereovision. To conclude, the rotational and translational amounts of orthodontic tooth movement could be measured directly from the patient with the marked brackets using stereovision system. This provides a foundation to relate tooth movement with orthodontic force for the investigation of orthodontic mechanism.
Key words: stereovision, orthodontic tooth movement, orthodontic force

INTRODUCTION
Although, clinically, orthodontic tooth treatment possesses a high success rate, the mechanism of tooth movement induced by orthodontic force remains unclear. Dental cast or cone-beam computed tomography (CBCT) has been applied to measure the tooth movement under orthodontic force. However, the measured data provides insufficient information, lack of integrated force data, to understand the mechanism. Previous study[16] has employed stereovision to measure tooth movement under orthodontic treatment. Force data was correlated with the measured movement to identify the relationship between tooth movement and orthodontic force using finite element simulation. However, only tooth translation was measured, tooth rotation was neglected during simulation. The specific aims of this study were (1) to measure and describe tooth movement, including both translation and rotation, with the stereovision system in clinical follow-ups; (2) to build the artificial tooth models, based on the 3D scanning at different stages, to measure the orthodontic force with six-axis load cell and related to the movement data.

MATERIALS AND METHODS
Stereovision system setup and accuracy evaluation:
The stereovision system was established using two cameras (D3200, Nikon, Tokyo, Japan), with relative position calibrated, to capture the orthodontic tooth position at different treatment stages. Both cameras were connected to a cable releaser so that pictures could be captured simultaneously. To secure the relative position of the subject and camera, head of the subject was placed on a customized holder. Four markers were burned on the four corners of a bracket using laser. The location of the orthodontic tooth at any stages was then determined using the reconstructed 3D coordinates of these marker brackets with the stereovision system. The accuracy of this approach was evaluated by cementing three brackets on a caliper (resolution of 0.01 mm), as shown in Figure A. In the figure, bracket 1 was cemented onto the left side of the caliper while Brackets 2 and 3 were cemented onto the right side of the caliper. As the caliper moved by 0 mm, 0.5 mm, 1 mm, 1.5 mm, and 2 mm respectively, the distance between Bracket 1 and Bracket 2 should reflect the caliper movement while the distance between Bracket 2 and Bracket 3 should remain constant. The measured distances, by the stereovision system, between each pair of brackets could be used to justify the accuracy of the stereovision system.

Patient follow up:
In this study, one patient was recruited for orthodontic treatment observation during a two months follow-up period. The lower central incisor, 41, was the tooth to be treated. Three brackets were cemented respectively onto central incisor, lateral incisor, 42, and canine, 43. A .016 × .022 inch stainless steel wire as well as the ligature wires were used to tie the brackets on 42 and 43 so that these two tooth were served as an anchor unit. Orthodontic force was applied on 41 with a Nitinol wire as shown in Figure B. Stereo pictures were taken before and immediately after the application of the force, as well as after 1, 4, 5, and 10 hours fof force applied. Thereafter for every 100 hours, pictures were taken by the stereovision system till 1,400 hours after force applied. The relapse process was also observed before and immediately after force termination, as well as after 1, 2, 4, 24, and 100 hours of relapsing.

Bracket orientation and position:
After obtain the 3D coordinates in the camera coordination system of the four laser marked points, the bracket position was represented by the mean of these four markers. Subsequently, a plane was fitted with these four markers to represent the orientation of the bracket in order to describe the bracket rotation.

Measurement of tooth movement and rotation:
To describe the tooth movement, a base coordinate system obtained from the brackets on the anchor teeth was established and this base coordinate system was assumed to be immovable during the orthodontic treatment. To build this coordinate system, a reference plane was fitted with the eight markers on the bracket of 42 and 43 to represent the XY plane. The mean of these eight markers was selected as the original of the base coordinate system. The measured camera coordinate data at each stage were transferred to this base coordinate system, that is superimposed pictures from different stages by aligning the brackets on 42 and 43 so that the tooth movement of 41 can be calculated. To measuring the tooth rotation, the bracket positions of 41 at different stages were further superimposition and the orientation difference of 41 brackets at different stages were used to calculate the rotation.

Measurement of orthodontic force:
The orthodontic force was measured using a 6-axis load cell with an artificial model made from 3D printing. The artificial models were reconstructed based the 3D scanning data after 1, 200, 400, and 1,200 hours of force applied and printed using an MOD 3D printer. The six-load cell was fixed onto a holder designed within the model. Three brackets were cemented onto the artificial model, the same as the clinical practice as shown in Figure C. After the Nitinol wire was applied the force and torque were recorded.

RESULTS AND DISCUSSION
The accuracy evaluation revealed that the stereovision measurement system has a maximum error less than 2%. It noted that this accuracy was affected mostly by the camera resolution and the quality of the picture which influence the laser markers identification from pictures. For the patient observation, the lateral incisor 41 moved about 0.9 mm during 1,400 hours (60 days) of tracking. The movement could be identified as a three-phase movements, a maximum of 0.5 mm movement during the first day, PDL visco-elastic deformation. Then the movement almost stationary till roughly 30 days the movement increased linearly to 0.9mm in another 30 days, bone remodeling phase. After 100 hours of removing the the NiTinol wire, the tooth was relapsed by 0.5 mm (0.4 mm was observed within the first day). Observed from occlusal to gingival, tooth 41 rotated clockwise 7 degrees, this rotation direction is consistent with the treatment planning from a clinical point of view. The results indicated that qualitatively the observed tooth movement and rotational were consisted with the clinical situation. Orthodontic force evaluations from artificial models shown that the average orthodontic force was around 0.5N, the same order of clinical practice.

CONCLUSION
To conclude:
(1) The orthodontic tooth movement, both translation and rotation, could be described by a stereovision system with laser-markered brackets.
(2) Using artificial models from 3D scanner and 3D printer to integrate with six-axis load cell, orthodontic force could be quantitative measured in vitro.
This system provides a foundation to Integrating tooth movement tracking data with the applied orthodontic f orce to investigate the mechanism of orthodontic treatment.
論文目次 目錄
中文摘要 I
Extended Abstract II
誌謝 IX
目錄 X
表目錄 XII
圖目錄 XII
第一章 緒論 1
1.1研究背景 1
1.2文獻回顧 2
1.2.1 測量牙齒移動 2
1.2.2光學測量系統 3
1.3立體影像 4
1.4研究動機 5
1.4.1 研究目的 5
第二章 材料與方法 6
2.1系統架設 6
2.1.1 相機校正 8
2.1.2立體系統精確度評估 9
2.1.3臨床病患追蹤 10
2.2影像對位 12
2.2.1主平面之建立 12
2.2.2 重疊影像之步驟 12
2.3 抵抗中心(center of resistance)之建立 15
2.4牙齒旋轉 18
2.5力量測量流程圖 21
2.5.1荷重元 22
2.5.2建立體外模型夾具設計 22
2.5.3矯正力測量步驟 23
第三章 結果 24
3.1立體影像系統準確性之評估 24
3.2 牙齒的移動及旋轉 25
3.3矯正力測量 30
第四章 討論 32
4.1立體影像系統 32
4.1.1立體影像系統之評估 32
4.1.2 標記點位置 33
4.1.3系統限制 34
4.2臨床追蹤 35
4.2.1由定性來觀測 35
4.2.2位移及角度定量分析 35
4.3矯正力與矯正器座標系位移量 37
第五章 結論 40
第六章 參考文獻 41
附錄一、相機校正 43
附錄二、Matlab相機校正操作 47
附錄三、角度準確性測量 50
表目錄

表3.1 立體影像測量及游標卡尺測量之比較(單位:mm) 25
表3.2四個不同時間點的矯正力測量 31
附錄表1 第一行為量角器所調整的角度變化量,二至四行為立體影像所測量之 52
x、y及z角度分量(單位:度) 52
附錄表2 第一行為量角器所調整的角度變化量,二和第四行為假設x軸及z軸方向的角度為零食的誤差,第三行為量角器量測角度扣相機量測角度之誤差(單位:度) 52
圖目錄
Figure. Abstract A. Caliper with three brackets, B. Tooth with three brackets, VIII
C. Artificial model with three brackets VIII
圖1.1 矯正牙齒移動過程 2
圖1.2 在不同矯正力的條件下,牙周韌帶的應力分布。 2
圖2.1 A.快門線,B.標有四個鐳射點的矯正器 6
圖2.2 立體影像系統架設 7
圖2.3 相機校正之流程 8
圖2.4 安裝三顆矯正器於游標卡尺上 9
圖2.5由俯視觀察受試者下顎齒的排列狀況 10
圖2.6 受試者待觀察之牙齒由右至左分別是前門齒#41、側門齒#42及犬齒#43,A.為.016x.022 英寸的不鏽鋼方線,B.為鎳汰合金線,C、為O型環。 11
圖2.7追蹤時間軸 11
圖2.9 A. 矯正器上,4個標記點之三維位置,B. 利用主平面分析法建立之直角坐標(紅:x綠:y藍:z) 12
圖2.10 A.透過8個點建立之參考座標系,描述三個矯正器位置,B. 將不同時間點的資料疊加於參考坐標系上。 13
本實驗為了觀察第三顆矯正器之位置,利用初始矯正器位置,建立一個新座標系(圖2.11A.1),用於描述第三矯正器平面之位置,將初始位置為基準點,可以計算出第三顆矯正器在不同時間點所改變之數值(圖2.11B)。 13
圖2.11 A.前視圖,B.上視圖,1.初始位置,2.其他時間點之位置 14
圖2.12 A.前門齒#41數位口掃影像,B.透過數位口掃影像建立矯正器模型,C.重疊A和B,D.重疊A和CBCT建立之前門齒#41,E.疊加完成之模型。 16
圖2.13 圖2-9C重疊結果。 16
圖2.14 圖2-9D重疊結果。 16
圖2.15 A.數位相機拍攝前門齒#41之矯正器,B.建立一正方形平面於矯正器模型上,C.透過重疊影像A和B建立雷射點相對位置,D. 4個標記點於型上之位置。 17
圖2.16 A.建立矯正器之座標系及牙齒之長軸,B.建立牙齒之座標系,C.抵抗中心於牙齒的位置。 17
圖2.17 牙齒在解剖位置上描述旋轉的名稱 18
圖2.18 A.矯正器座標系(Bracket coordinate system),B.牙齒坐標系(Tooth coordinate system) 19
圖2.19疊加兩組不同時間之座標系,計算出θx、θy、θz 分別的角度。 20
圖2.20體外力量測量流程圖 21
圖 2.21 A. Nano 17,B. Force/Torque Sensor Controller System 22
圖 2.22 夾具模型 22
圖 2.23 A. MakerBot replicator 2x,B. 夾具 23
圖 2.24 荷重元的固定 23
圖3.1牙齒總位移量及分量(矯正器座標系) 26
圖3.2 釋放矯正力後前門齒的總位移量及分量(矯正器座標系) 26
圖3.3 前門齒矯正過程中角度變化量(矯正器座標系) 27
圖3.4前門齒移除矯正後的角度變化量(矯正器座標系) 27
圖3.5 每100小時前門齒的移動量(矯正器座標系) 28
圖3.6 移除矯正力後前門齒在每一個記錄時間點的移動量(矯正器座標系) 28
圖3.7牙齒總位移量及分量(牙齒座標系) 29
圖3.8前門齒矯正過程中角度變化量(牙齒座標系) 29
圖3.9 利用六軸感測器測量四個不同時間點的力量 31
圖3.10 利用六軸感測器測量四個不同時間點的力矩 31
圖4.1 A.使用三顆13w的白燈泡,增加口內的亮度,B.固定頭部的架子,黑色部分是泡綿軟墊。 33
圖4.2A.未補光所拍攝之矯正器,B.補光後所拍率之矯正器。 33
圖4.3 利用主平面分析法建立之直角座標系 34
圖4.4 較矯正器座標系原點位置Z方向的改變量與牙齒座標系抵抗中心Z方向的改變量 36
圖4.5 追蹤前期10-30小時牙齒坐標系(抵抗中心)的位移改變量Y、Z及Torque的改變量. 36
圖4.6 追蹤前期600-800小時牙齒坐標系(抵抗中心)的位移改變量Y、Z及Torque的改變量 37
圖4.7位移與矯正力比較: A. X方向位移與Fx方向矯正力,B. Y方向位移與Fy方向矯正力,C. Z方向位移與Fz方向矯正力,D. 前門齒Y-Z方向示意圖 39
圖4.8旋轉與力距比較: A. Torque方向旋轉與Mx力矩,B. Rotation方向旋轉與My力矩,C. Angulartion方向旋轉與Mx力矩,D. 前門齒Y-Z方向示意圖 39
附錄圖A.1 相機校正過程 43
附錄圖A.2針孔成像原理 44
附錄圖A.3 pinhole camera model 45
附錄圖A.4 相機坐標系與外部坐標系連結方式 46
附錄圖B.1 Camera Calibration Toolbox GUI_1 47
附錄圖 B.2 Camera Calibration Toolbox GUI_2 47
附錄圖B.3 Camera Calibration Toolbox GUI_ stereo 48
附錄圖B.4選取網格的邊角,透過Toolbox 中的Stereo Camera Calibration將校正兩台校正後空間座標的資訊進行整合。 48
附錄圖B.5校正結果 49
附錄圖B.6立體校正結果 49
附錄圖C.1 評估角度測量準確性之系統,包含3個矯正器、量角器、底座及3D列印模型。 51

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