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系統識別號 U0026-2608201904500100
論文名稱(中文) 長距離跑對於成年男性骨質密度影響之整合分析研究
論文名稱(英文) The effects of long-distance running on bone mineral density in adult males: A meta-analysis
校院名稱 成功大學
系所名稱(中) 體育健康與休閒研究所
系所名稱(英) Institute of Physical Education, Health & Leisure Studies
學年度 107
學期 2
出版年 108
研究生(中文) 萬子翟
研究生(英文) Steve Wann
學號 RB6031024
學位類別 碩士
語文別 中文
論文頁數 66頁
口試委員 指導教授-黃滄海
口試委員-林麗娟
口試委員-余聰
中文關鍵字 數據分析  跑者  系統性回顧文獻  效應值 
英文關鍵字 data analysis  runner  systematic review  effect size 
學科別分類
中文摘要 背景:長距離跑步運動與骨質密度之間的關係在過去的研究結果中有明顯的歧異,使得長距離跑步運動對骨質密度的影響一直未能被確認。

目的:本研究希望透過整合分析 (meta-analysis) 方法來探討長距離跑步運動對骨質密度的影響。

方法:本研究根據Cochrane系統性回顧文獻操作手冊所制定的步驟執行此研究。經由PICO模型制定出選取標準:「成年男性」、「18至65歲」、「參與長距離跑步運動者」與「相同條件不運動者」。透過耐力、骨質密度相關的關鍵字從Embase、Medline、Scopus三個資料庫中,搜尋到988篇相關文獻,並依據選取標準,經由標題、摘要、全文、質性分析等步驟篩選後,最後剩餘23篇文獻使用Review Manager 5.3版本軟體進行整合分析,並依據結果進行敏感度分析。由於各文獻所測量的骨質密度部位不盡相同,因此本研究分為全身 (total body)、脊椎 (spine)、髖部 (hip)、上肢 (upper limb)、下肢 (lower limb) 五個部位進行整合分析,並取各文獻在前述五個部位所測量之最大區塊骨質密度歸為該部份之骨質密度,由於各研究所測量之部位不同,因此使用標準化平均數差異 (standardized mean difference) 計算綜合效應。為避免文獻間異質性影響結果判斷,本研究採用隨機式模型 (random-effects model)。

結果:長距離跑步運動能顯著增加成年男性長距離跑者全身(綜合效應95%信賴區間[0.05, 0.62])、下肢骨質密度(綜合效應95%信賴區間[0.41, 0.74])及髖部的骨質密度(綜合效應95%信賴區間[0.18, 0.69]),對上肢(綜合效應95%信賴區間[-0.47, 0.28])、脊椎(綜合效應95%信賴區間[-0.23, 0.31])則沒有顯著影響。

結論:長距離跑步運動對成年男性骨質密度有正面影響,但其效應有部位上的差異。未來探討相關議題時,需分部位討論。
英文摘要 Purpose: Use Meta-analysis to find out the relation between long-distance running and bone mineral density (BMD).

Method: Based on Cochrane’s systematic review handbook, we used the PICO model to identify our selection criteria as follows: adult males, aged 18 to 65, long-distance runner, and non-exercise males as a control group. By using keyword searching studies from Embase, Medline, and Scopus, 988 studies were found, of which twenty-three studies were selected according to their titles, abstracts, full texts and the agreement by all the researchers in the present study. In these twenty-three studies, analysis was conducted on BMD data from five categories: total body, spine, hip, upper limb, and lower limb. The random-effects model is used to avoid heterogeneity.

Result: Long-distance running significantly increases total BMD, lower limb BMD and hip BMD in elite male runners, but there is no difference between long-distance running group and control group in upper limb BMD and spine BMD.

Conclusion: Long-distance running shows positive effects on bone mineral density, but the effects are site-specific. Future research needs to be aware that different sites may have different effects.
論文目次 中文摘要 I
SUMMARY II
謝誌 VI
目錄 VII
表目錄 IX
圖目錄 X
第壹章 緒論 1
 第一節 研究背景 1
 第二節 研究目的 2
 第三節 名詞操作型定義 2
第貳章 文獻探討 4
 第一節 骨質密度:評估骨頭健康的重要指標 4
 第二節 性別、年齡與運動和骨質密度之間的關係 5
 第三節 長距離跑者的骨質密度 6
 第四節 長距離跑的定義 8
 第五節 總結 9
第參章 研究方法 10
 第一節 PICO模型 10
 第二節 設定納入資訊與文獻篩選條件 11
 第三節 確立搜尋資料庫與關鍵字 11
 第四節 篩選文獻 13
 第五節 資料萃取與整理 14
 第六節 數據分析 16
第肆章 研究結果 17
 第一節 文獻檢索 17
 第二節 部位分類 18
 第三節 納入文獻偏差風險分析 18
 第四節 整合分析 30
 第五節 敏感度分析 33
 第六節 出版偏差 36
第伍章 討論 38
 第一節 長距離跑與全身骨質密度 38
 第二節 長距離跑與脊椎骨質密度 39
 第三節 長距離跑與髖部骨質密度 40
 第四節 長距離跑與上肢骨質密度 41
 第五節 長距離跑與下肢骨質密度 42
 第六節 綜合討論 44
 第七節 研究限制 46
第陸章 結論與建議 48
 第一節 結論 48
 第二節 未來研究建議 48
參考資料 50
附錄 56
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