進階搜尋


   電子論文尚未授權公開,紙本請查館藏目錄
(※如查詢不到或館藏狀況顯示「閉架不公開」,表示該本論文不在書庫,無法取用。)
系統識別號 U0026-1908201821103900
論文名稱(中文) 含NMP半導體廢水在好氧,缺氧與厭氧條件下之生物可降解性評估之研究
論文名稱(英文) Potential of Biological N-Methylpyrrolidone (NMP) Removal in Semiconductor Wastewater under Aerobic, Anoxic and Anaerobic Conditions
校院名稱 成功大學
系所名稱(中) 環境工程學系
系所名稱(英) Department of Environmental Engineering
學年度 106
學期 2
出版年 107
研究生(中文) 丘恬鳳
研究生(英文) Natalia Diani Triana
電子信箱 aurelinatalia@outlook.com
學號 P56057074
學位類別 碩士
語文別 英文
論文頁數 89頁
口試委員 口試委員-張嘉修
口試委員-林財富
口試委員-鄭幸雄
指導教授-黃良銘
中文關鍵字 "none" 
英文關鍵字 NMP  semiconductor wastewater  biological treatment  aerobic  anoxic  anaerobic 
學科別分類
中文摘要 "none"
英文摘要 The thriving growth of semiconductor industry in this digital era is also accompanied by increase of dangerous wastewater produced containing high concentration of organic compounds, including NMP which generally takes part as photoresist stripper solvent. Even though previously NMP was considered as benign alternative and has no severe risk to environment, but later was found as reproductive and developmental toxin. In this study, potential of biological NMP removal from semiconductor wastewater using aerobic, anoxic and anaerobic conditions was evaluated. Laboratory scale of aerobic MBR system was developed to resemble real wastewater treatment plant condition. Additionally, several batch assays were also conducted to evaluate behaviors of NMP removal process in each conditions with different initial concentrations. Stable and effective removal of NMP as high as 99% was successfully achieved using aerobic MBR as well as in aerobic batch experiment. Moreover, this removal process of NMP apparently could be reach up to mineralization process. Higher tolerance to higher NMP loading was also shown in this condition compared to others. Nevertheless, great potential of NMP removal was also shown in anoxic condition, especially in low concentration, and faster NMP degradation rate for each subsequent runs could be achieved. On the other hand, in this study, biological NMP removal could not be effectively achieved in anaerobic condition. Despite of the effectiveness, some limitations shown in each aerobic and anoxic conditions. In aerobic, presence of NMP inhibited nitrification process (total inhibition possibly occurred in high NMP loading) which therefore followed by ammonia accumulation. Meanwhile, in anoxic conditions some intermediates that could not be further biologically removed might remained in system, which indicated different NMP degradation pathway between aerobic and anoxic condition possibly occurred.
論文目次 ABSTRACT i
ACKNOWLEDGEMENT iii
LIST OF CONTENT v
LIST OF TABLES vii
LIST OF FIGURES ix
CHAPTER 1 INTRODUCTION 1
CHAPTER 2 LITERATURE REVIEW 3
2.1 Semiconductor Wastewater 3
2.2 NMP Usage 4
2.3 NMP Biodegradation 6
2.4 Membrane Bioreactor 10
2.5 Nitrogen 13
2.5.1. Nitrogen Cycle 13
2.5.2. Ammonification 15
2.5.3. Nitrification 16
2.5.4. Denitrification 17
CHAPTER 3 MATERIALS AND METHODS 19
3.1 Semiconductor Wastewater 19
3.2 Operational Condition of Aerobic Membrane Bioreactor (MBR) 21
3.3 Batch Assays 23
3.3.1. Aerobic Condition 24
3.3.2. Anoxic Condition 25
3.3.3. Anaerobic Condition 27
3.4 Analytical Methods 29
3.4.1. General Chemical Analytical Methods 29
3.4.2. Instrumental Analytical Methods 30
CHAPTER 4 RESULTS AND DISCUSSION 33
4.1 Aerobic Biological NMP Removal 33
4.1.1. Lab-Scale Biological Membrane Bioreactor (MBR) under Continuous Operation 33
4.1.2. NMP Aerobic Biodegradation Batch Assays 39
4.1.3. Summary of NMP Biological Removal in Aerobic Condition 51
4.2 NMP Anoxic Biodegradation Batch Assays 52
4.3 NMP Anaerobic Biodegradation Batch Assays 70
CHAPTER 5 CONCLUSION AND SUGGESTIONS 83
5.1. Conclusion 83
5.2. Suggestion 84
REFERENCES 85
參考文獻 Akesson, B., Jonsson, B.A.G. Major Metabolic Pathway for NMP in Humans. Drug Metabolism and Disposition, 25. 1997.
Apha, A. WPCF, 1998. Standard methods for the examination of water and wastewater, 20. 1998.
Bader, M., Rosenberger, W., Rebe, T., Keener, S.A., Brock, T.H., Hemmerling, H.J., Wrbitzky, R. Ambient monitoring and biomonitoring of workers exposed to N-methyl-2-pyrrolidone in an industrial facility. Int Arch Occup Environ Health, 79(5), 357-64. 2006.
Beaulieu, H.J., Schmerber, K.R. M-Pyrol™ (NMP) Use in the Microelectronics Industry. Applied Occupational and Environmental Hygiene, 6(10), 874-880. 1991.
Bernhard, A. The Nitrogen Cycle : Processes, Players and Human Impact. Nature Education Knowledge 3(10). 2010.
Bont, J.A.M.D., Dijken, J.P.V., Harder, W. Dimethyl Sulphoxide and Dimethyl Sulphide as a Carbon, Sulphur and Energy Source for Growth of Hyphomicrobium S. Journal of General Microbiology, 315-323. 1981.
Bower, D.B. Stillbirth after occupational exposure to N-methyl-2 pyrrolidone. Journal of occupational and environmental medicine, 39(5), 393. 1997.
Burghate, S.P., Ingole, D.N.W. Biological Denitrification - A Review. Journal of Environmental Science, Computer Science and Engineering & Technology, 3, 009-028. 2013.
Cai, S., Cai, T., Liu, S., Yang, Q., He, J., Chen, L., Hu, J. Biodegradation of N-Methylpyrrolidone by Paracoccus sp. NMD-4 and its degradation pathway. International Biodeterioration & Biodegradation, 93, 70-77. 2014.
Campbell, H.L., Striebig, B.A. Evaluation of NMP and Its Oxidative Products Toxicity Utilixing the Microtox Assay. Environmental Science Technology, 33, 1926-1930. 1999.
Carnerup, M.A., Saillenfait, A.M., Jonsson, B.A. Concentrations of N-methyl-2-pyrrolidone (NMP) and its metabolites in plasma and urine following oral administration of NMP to rats. Food Chem Toxicol, 43(9), 1441-7. 2005.
Carnerup, M.A., Spanne, M., Jonsson, B.A. Levels of N-methyl-2-pyrrolidone (NMP) and its metabolites in plasma and urine from volunteers after experimental exposure to NMP in dry and humid air. Toxicol Lett, 162(2-3), 139-45. 2006.
Chen, J., Ying, G.G., Liu, Y.S., Wei, X.D., Liu, S.S., He, L.Y., Yang, Y.Q., Chen, F.R. Nitrogen removal and its relationship with the nitrogen-cycle genes and microorganisms in the horizontal subsurface flow constructed wetlands with different design parameters. J Environ Sci Health A Tox Hazard Subst Environ Eng, 52(8), 804-818. 2017.
Chen, S.Y., Lu, L.A., Lin, J.G. Biodegradation of tetramethylammonium hydroxide (TMAH) in completely autotrophic nitrogen removal over nitrite (CANON) process. Bioresour Technol, 210, 88-93. 2016.
Chen, T.K., Ni, C.H., Chen, J.N. Nitrification–Denitrification of Opto-electronic Industrial Wastewater by Anoxic/Aerobic Process. Journal of Environmental Science and Health, Part A, 38(10), 2157-2167. 2003.
Chow, S.T., Ng, T.L. The Biodegradation of N-Methyl-2-Pyrrolidone In Water by Sewage Bacteria. Water Resource, 17(1), 117-118. 1983.
Constable, D.J.C., Dunn, P.J., Hayler, J.D., Humphrey, G.R., Leazer, J.J.L., Linderman, R.J., Lorenz, K., Manley, J., Pearlman, B.A., Wells, A., Zaks, A., Zhang, T.Y. Key green chemistry research areas—a perspective from pharmaceutical manufacturers. Green Chem., 9(5), 411-420. 2007a.
Constable, D.J.C., Jimenez-Gonzalez, C., Henderson, R.K. Perspective on Solvent Use in the Pharmaceutical Industry. Organic Process Research & Development 11, 133-137. 2007b.
Den, W., Ko, F.-H., Huang, T.-Y. Treatment of Organic Wastewater Discharged From Semiconductor Manufacturing Process by Ultraviolet/Hydrogen Peroxide and Biodegradation. IEEE Transactions on Semiconductor Manufacturing, 15, 540-551. 2002.
Dentinger, P.M., Clift, W.M., Goods, S.H. Removal of SU-8 photoresist for thick film applications. Microelectronic Engineering, 61-62, 993-1000. 2002.
Dvorak, L., Svojitka, J., Wanner, J., Wintgens, T. Nitrification performance in a membrane bioreactor treating industrial wastewater. Water Res, 47(13), 4412-21. 2013.
Fan, X.-J., Urbain, V., Qian, Y., Manem, J. Nitrification and Mass Balance with a Membrane Bioreactor for Municipal Wastewater Treatment. Water Science and Technology, 34(1-2), 129-136. 1996.
Flick, B., Talsness, C.E., Jackh, R., Buesen, R., Klug, S. Embryotoxic potential of N-methyl-pyrrolidone (NMP) and three of its metabolites using the rat whole embryo culture system. Toxicol Appl Pharmacol, 237(2), 154-67. 2009.
Fu, Z., Yang, F., An, Y., Xue, Y. Simultaneous nitrification and denitrification coupled with phosphorus removal in an modified anoxic/oxic-membrane bioreactor (A/O-MBR). Biochemical Engineering Journal, 43(2), 191-196. 2009.
Gonzales, C.J.S., Malfavon, L.D., Suarez, M.V., Gaytan, I., Cevallos, M.A., Lozano, L., Gomez, M.J.C., Tavera, H.L. Novel Metabolic Pathway for N-Methylpyrrolidone Degradation in Alicycliphilus sp. Strain BQ1. Applied and Environmental Microbiology, 84(1). 2018.
Jouyban, A., Fakhree, M.A.A., Shayanfar, A. Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone. Journal of Pharmacy and Pharmaceutical Sciences, 13(4), 524-535. 2010.
Krizek, K., Ruzicka, J., Julinova, M., Husarova, L., Houser, J., Dvorackova, M., Jancova, P. N-methyl-2-pyrrolidone-degrading bacteria from activated sludge. Water Sci Technol, 71(5), 776-82. 2015.
Lan, C.H., Peng, C.Y., Lin, T.S. Acute aquatic toxicity of N-methyl-2-pyrrolidinone to Daphnia magna. Bull Environ Contam Toxicol, 73(2), 392-7. 2004.
Lee, J.K., Lee, W.J., Cho, Y.-J., Park, D.H., Lee, Y.-W., Chung, J. Variation of bacterial community immobilized in polyethylene glycol carrier during mineralization of xenobiotics analyzed by TGGE technique. Korean Journal of Chemical Engineering, 27(6), 1816-1821. 2010.
Lei, C.N., Whang, L.M., Chen, P.C. Biological treatment of thin-film transistor liquid crystal display (TFT-LCD) wastewater using aerobic and anoxic/oxic sequencing batch reactors. Chemosphere, 81(1), 57-64. 2010.
Lei, C.N., Whang, L.M., Lin, H.L. Biological treatment of thin-film transistor liquid crystal display (TFT-LCD) wastewater. Water Sci Technol, 58(5), 1001-6. 2008.
Loh, C.H., Wu, B., Ge, L., Pan, C., Wang, R. High-strength N-methyl-2-pyrrolidone-containing process wastewater treatment using sequencing batch reactor and membrane bioreactor: A feasibility study. Chemosphere, 194, 534-542. 2018.
Lu, H., Chandran, K., Stensel, D. Microbial ecology of denitrification in biological wastewater treatment. Water Res, 64, 237-254. 2014.
Mateju, V., Cizinska, S., Krejci, J., Janoch, T. Biological water denitrification - A review. Enzyme and Microbial Technology, 14(3), 170-183. 1992.
Oceguera-Cervantes, A., Carrillo-Garcia, A., Lopez, N., Bolanos-Nunez, S., Cruz-Gomez, M.J., Wacher, C., Loza-Tavera, H. Characterization of the polyurethanolytic activity of two Alicycliphilus sp. strains able to degrade polyurethane and N-methylpyrrolidone. Appl Environ Microbiol, 73(19), 6214-23. 2007.
Park, S.-J., Yoon, T.-I., Bae, J.-H., Seo, H.-J., Park, H.-J. Biological treatment of wastewater containing dimethyl sulphoxide from the semi-conductor industry. Process Biochemistry, 36, 579-589. 2001.
Pastore, B.M., Savelski, M.J., Slater, C.S., Richetti, F.A. Life cycle assessment of N-methyl-2-pyrrolidone reduction strategies in the manufacture of resin precursors. Clean Technologies and Environmental Policy, 18(8), 2635-2647. 2016.
Reisch, M. Solvent users look to replace NMP. Chemical & Engineering News, 86(29), 32. 2008.
Ruzicka, J., Fuskova, J., Krizek, K., Merkova, M., Cernotova, A., Smelik, M. Microbial degradation of N-methyl-2-pyrrolidone in surface water and bacteria responsible for the process. Water Sci Technol, 73(3), 643-7. 2016.
Ryu, H.D., Kim, D., Lee, S.I. Application of struvite precipitation in treating ammonium nitrogen from semiconductor wastewater. J Hazard Mater, 156(1-3), 163-9. 2008.
Shen, C.-w., Tran, P., Minh Ly, P. Chemical Waste Management in the U.S. Semiconductor Industry. Sustainability, 10(5), 1545. 2018.
SIA, S.I.A. SIA Comments to EPA on N-Methylpyrrolidone (NMP). 2017.
Solomon, G., P. Morse, E., J. Garbo, M., Milton, D. Stillbirth after Occupational Exposure to N-Methyl-2Pyrrolidone: A Case Report and Review of the Literature. 1996.
Stein, L.Y., Klotz, M.G. The nitrogen cycle. Curr Biol, 26(3), R94-8. 2016.
Sutton, P.M. Membrane bioreactors for industrial wastewater treatment: Applicability and selection of optimal system configuration. Proceedings of the Water Environment Federation, 2006(9), 3233-3248. 2006.
Taylor, B.F., Kiene, R.P. Microbial Methabolism of Dimethyl Sulfide. In Biogenic Sulfur in the Environment, ACS Symposium Series 1989.
Wintgens, T., Rosen, J., Melin, T., Brepols, C., Drensla, K., Engelhardt, N. Modelling of a membrane bioreactor system for municipal wastewater treatment. Journal of Membrane Science, 216(1-2), 55-65. 2003.
Wood, P.M. The Redox Potential For Dimethyl Sulphoxide Reduction to Dimethyl Sulphide : Evaluation and biochemical implications. FEBS Letters, 124(1), 11-14. 1981.
Zinder, S.H., Brock, T.D. Dimethyl Sulphoxide Reduction by Micro-organisms Journal of General Microbiology, 105, 335-342. 1978.
Zolfaghari, A., Mortaheb, H.R., Meshkini, F. Removal ofN-Methyl-2-pyrrolidone by Photocatalytic Degradation in a Batch Reactor. Industrial & Engineering Chemistry Research, 50(16), 9569-9576. 2011.
論文全文使用權限
  • 同意授權校內瀏覽/列印電子全文服務,於2023-12-31起公開。
  • 同意授權校外瀏覽/列印電子全文服務,於2023-12-31起公開。


  • 如您有疑問,請聯絡圖書館
    聯絡電話:(06)2757575#65773
    聯絡E-mail:etds@email.ncku.edu.tw