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系統識別號 U0026-1507201317484400
論文名稱(中文) 影響從眾行為之生物因素
論文名稱(英文) Biological Factors Affecting Behavioral Conformity
校院名稱 成功大學
系所名稱(中) 行為醫學研究所
系所名稱(英) Institute of Behavioral Medicine
學年度 101
學期 2
出版年 102
研究生(中文) 王菁憶
研究生(英文) Ching-Yi Wang
學號 s86004062
學位類別 碩士
語文別 英文
論文頁數 47頁
口試委員 指導教授-游一龍
口試委員-任卓穎
口試委員-郭余民
中文關鍵字 從眾行為  性別差異  Fos 
英文關鍵字 conformity behavior  sex difference  Fos 
學科別分類
中文摘要 為瞭解從眾行為的發生原因,我們提出了一個具演化、生物基礎且命名為”相似”的假設。在所有會展現出社交行為的物種中,群體中的個體之所以會表現從眾行為,我們假設是因為群體內每一個成員皆具有極相似的對危險的覺察系統以及對危險的反應系統。因此,我們預期從眾行為會因為可預期的高度風險而有所增加,不論預期風險出現的機率維持一致或個體是否為團體中的一員這兩個過去假設的因素;我們也預期對於團體的熟悉度並不會影響到從眾行為的表現。我們建立了小鼠的兩個從眾行為模式。第一個模式在比較實驗小鼠於單獨或是有同伴陪伴的情境下,在自製彎臂T字迷宮中所花費的時間。另一從眾行為模式,主要在計算實驗小鼠於單獨或是有同伴陪伴的情境下之正確選擇率。結果發現,小鼠的從眾行為,會因為可預期的高度風險而增加。這個結果和過去的假設衍生的預測不合,但完全支持我們的”相似”假設。而在其中一個小鼠從眾行為模式中我們發現到小鼠的從眾行為是具有性別差異的。在同伴陪伴的情境下,雄鼠比雌鼠更容易受到同性別同伴的影響。最後,陪伴的同伴之熟悉程度並不會影響到個體從眾行為的發生。我們進一步利用已建立好之小鼠從眾行為模式、立體定位儀手術與Fos染色定量技術,試著去找尋和小鼠從眾行為表現調控有所相關的腦區。我們雖然發現以lidocaine局部注入nucleus accumbens及striatum兩個過去研究中認為和從眾行為有關的腦區,並不會影響從眾行為的表現,但Fos的結果指出部分腦區神經元的活性似乎能反應出從眾行為展現的強度。
英文摘要 In an attempt to understand the causes of behavioral conformity, a “resemblance” hypothesis has been provided. The “resemblance” hypothesis posits that any member of a social species displays behavioral conformity within the group because all members possess extremely similar risk-perceiving and risk-responding systems. Accordingly, we predicted that the conformity of an individual may be enhanced by the evaluation of an anticipated, intense risk regardless of personal preference to group’s decision or consideration of personal involvement in the group. Moreover, we predicted that familiarity with the group might play a negligible role in modulating the behavioral conformity of the individual. A mouse conformity model was established by contrasting the differences in time spent navigating a maze when mice were alone versus when they were in a companion group. And we calculated the correct rate for the experimental mouse in another mouse conformity model. These results, taken together, support our resemblance hypothesis by indicating that behavioral conformity can be enhanced by an expected, intense risk. And in another model can find behavioral conformity has sex difference in mice. Specifically, male mice were more easily affected by the presence of companions than female mice. Moreover, familiarity with the conformity group and the social status did not seem to affect the behavioral conformity of the individual. Then, we use this mouse conformity model, stereotaxic surgery, and Fos-staining to find that was any specific brain regions regulate conformity behavior in mice. We found that, intra-nucleus accumbens or striatum infusions, this two brain regions might affect conformity behavior in past studies, would not affect conformity behavior in mice. The result of Fos-staining indicated that, parts of brain regions’ activation would be reacted about the conformity behavior’s exhibit.
論文目次 Table of Contents
Abstract (Chinese)………………………………………………………………1
Abstract (English)………………………………………………………………2
Introduction & hypothesis……………………………………………………6
Materials & methods………………………………………………………………9
 Animals
 Custom-made J-shaped maze
 Drug
 Stereotaxic surgery
 Behavioral procedure
 Immunohistochemistry
 Experimental design
 Statistical analysis
Results………………………………………………………………………………17
Discussion…………………………………………………………………………20
Reference……………………………………………………………………………22
Figure…………………………………………………………………………………24
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