進階搜尋


下載電子全文  
系統識別號 U0026-1307201417365000
論文名稱(中文) 電磁熱療系統之自調式模糊溫度控制
論文名稱(英文) Self-Tuning Fuzzy Temperature Control for Electromagnetic Thermotherapy System
校院名稱 成功大學
系所名稱(中) 電機工程學系
系所名稱(英) Department of Electrical Engineering
學年度 102
學期 2
出版年 103
研究生(中文) 戴書哲
研究生(英文) Shu-Jhe Tai
學號 N26010300
學位類別 碩士
語文別 中文
論文頁數 80頁
口試委員 指導教授-戴政祺
口試委員-黃世杰
口試委員-張益三
口試委員-江朝文
中文關鍵字 電磁熱療  感應加熱  自調式  模糊控制  量化因子  比例因子 
英文關鍵字 Electromagnetic Thermotherapy  Induction Heating  Self-Tuning  Fuzzy Control  Quantization Factor  Scale Factor 
學科別分類
中文摘要 電磁熱療是使用高頻感應加熱器於體外產生一交變磁場,並對腫瘤細胞周圍的磁性物質進行加熱,使磁性物質升溫達到不同組織部位治療所需要之溫度,藉此殺死腫瘤細胞並達到熱療之效果。本篇論文設計一模糊溫度控制器用於控制金屬針具之感應加熱溫度,並對腫瘤組織進行安全的燒灼治療。使用高速運算之微控制器做為數位控制核心,藉由模糊邏輯控制來辨別溫度誤差及溫度誤差變化量之幅度,並決策出適當的加熱頻率來控制感應加熱器的輸出功率,又因在實際腫瘤熱治療應用中金屬針具會因為人體呼吸起伏而改變距離,或因不同治療組織造成加熱負載變化,所以本文使用量化因子及比例因子自調式模糊控制器因應加熱負載的變化。經實驗結果證明,本文電磁熱療系統之自調式模糊溫度控制可在負載變動的情況下維持2 %以內的溫度誤差,較傳統的PID控制器更強健,使腫瘤熱治療更加安全。
英文摘要 Electromagnetic thermotherapy involves using a high-frequency induction heating machine to generate an alternating magnetic field that heats the magnetic materials surrounding tumor cells to the specific temperature required for treating various tissues. In this study, a fuzzy temperature controller was designed to control the induction heating temperatures of metallic needles. The proposed design enables performing safe ablation therapies on tumor tissues. Using a high-speed microcontroller as the digital control core, the proposed system determines temperature error and temperature error variations through fuzzy logic control. Subsequently, the system design determines the heating frequency required to control the power output of the induction heating machine. Because the distance between the metallic needles and target tissues vibrates with breathing when applying thermotherapy to tumor cells in practice, we employed fuzzy controllers featuring self-tuning quantization and scale factors to address changes in heating load. The experimental results demonstrated that the proposed electromagnetic thermotherapy system with fuzzy temperature control could maintain the temperature error within 2% under load variations. The results indicate that the designed system was more robust when compared with conventional proportional-integral-derivative (PID) controllers. Therefore, the proposed system can facilitate conducting safe thermotherapy on tumor cells.
論文目次 摘 要 I
Extended Abstract II
誌謝 VII
目錄 VIII
圖目錄 XI
表目錄 XV
第一章 緒論 1
1-1 研究背景 1
1-2 熱治療簡介 2
1-3 國內外文獻回顧 3
1-4 研究動機與目的 5
第二章 感應加熱原理及系統分析 6
2-1感應加熱原理 6
2-2串聯諧振式轉換器 7
2-2-1全橋串聯諧振轉換器架構 8
2-2-2全橋串聯諧振轉換器運作原理及分析 8
第三章 模糊控制器 11
3-1模糊理論基本概念 11
3-2模糊控制器架構 13
3-2-1 模糊化介面 13
3-2-2 模糊知識庫 15
3-2-3 模糊決策邏輯 15
3-2-4 解模糊化介面 17
3-3量化因子及比例因子自調式模糊控制器 18
3-3-1 自調式模糊控制器調變方法 18
3-3-2 量化因子與比例因子 18
3-3-3 量化因子及比例因子自調式模糊控制系統之設計 21
第四章 系統架構 28
4-1系統架構 28
4-2硬體電路設計 29
4-2-1 閘極隔離驅動電路 29
4-2-2 一次側CT回授整流濾波電路 30
4-2-3 溫度感測電路 33
4-3系統軟體架構 35
4-3-1 系統操作流程 35
4-3-2 模糊溫度控制器動作流程 37
4-4人機介面設計 38
第五章 模擬及實驗 40
5-1實驗系統架構 40
5-2模擬與實驗項目 42
5-2-1 PID控制器與模糊控制器加熱模擬 43
5-2-2 PID控制器與模糊控制器加熱實驗 51
5-2-3 腫瘤熱療應用之豬肝加熱實驗 59
5-3實驗結果與討論 65
第六章 結論與未來展望 74
6-1結論 74
6-2未來展望 75
參考文獻 76
自述 XVI
參考文獻 [1] 行政院衛生署,「99年死因統計結果 行政院衛生署」,原水文化出版社,2011。
[2] R. J. DeWall, T. Varghese, and C. L. Brace, "Quantifying Local Stiffness Variations in Radiofrequency Ablations With Dynamic Indentation," IEEE Transactions on Biomedical Engineering, Vol. 59, No. 3, pp. 728-735, March 2012.
[3] R. K. Gilchrist, R. Medal, W. D. Shorey, R. C. Hanselman, J. C. Parrot, C. B. Taylor, "Selective Inductive Heating of Lymph Nodes," Annals of Surgery, Vol. 146, pp. 596-606, October 1957.
[4] A. Jordan, R. Scholz, P. Wust, H. Fahling, J. Krause, W. Wlodarczyk, B. Sander, T. Vogl, and R. Felix, "Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo," Int. J. Hyperthermia, Vol. 13, No. 6, pp. 587-605, 1997.
[5] L. A. Barragan, D. Navarro, J. Acero, Isidro Urriza, and J. M. Burdio, "FPGA Implementation of a Switching Frequency Modulation Circuit for EMI Reduction in Resonant Inverters for Induction Heating Appliances," IEEE Transactions on Industrial Electrinics, Vol. 55, No. 1, January 2008.
[6] H. Fujita, N. Uchida, and K. Ozaki, "A New Zone-Control Induction Heating System Using Multiple Inverter Units Applicable under Mutual Magnetic Coupling Conditions," IEEE Trans. Power Electron., Vol. 26, No. 7, pp. 2009-2017, Jul. 2010.
[7] Y. L. CUI, K. HE, Z. W. FAN, H. L. FAN, "Study on DSP-based PLL-Controlled Superaudio Induction Heating Power Supply Simulation," Proceedings of the Fourth International Conference on Machine Learning and Cybernetics, Guangzhou, 18-21 August 2005.
[8] V. Esteve, E. Sanchis-Kilders, J. Jordan, E. J. Dede, E. J. Dede, C. Cases, E. Maset, J. B. Ejea, and A. Ferreres, "Improving the Efficiency of IGBT Series-Resonant Inverters Using Pulse Density Modulation," IEEE Trans. Ind. Electron., Vol. 58, No. 3, pp. 979-987, Mar. 2011.
[9] N. A. Ahmed, "High-Frequency Soft-Switching AC Conversion Circuit with Dual-Mode PWM/PDM Control Strategy for High-Power IH Applications," IEEE Trans. Ind. Electron., Vol. 58, No. 4, pp. 1440-1448, Apr. 2011.
[10] H. Sarnago, A. Mediano, and O. scar Lucia, "High Efficiency AC-AC Power Electronic Converter Applied to Domestic Induction Heating," IEEE Transactions On Power Electrionics, Vol. 27, No. 8, August 2012.
[11] C. C. Chen, C. C. Tai, S. J. Huang, Y. H. Chen, and C. H. Lin, "Thermotherapy Induction Heating Apparatus with New Magnetic-Wrapped Coil Design," IEEE Trans. Ind. Electron., Vol. 61, No. 5, May 2014.
[12] H. Sarnago, O. Lucia, A. Mediano, and J. M. Burdio, "Class-D/DE Dual-Mode-Operation Resonant Converter for Improved-Efficiency Domestic Induction Heating System," IEEE Trans. Power Electron., Vol. 28, No. 3, pp. 1274-1285, Mar. 2013.
[13] 陳明坤,「磁性奈米粒子熱治療系統」,國科會提案計畫報告,2006。
[14] 蕭正昌,「應用於腫瘤熱療之奈米磁粒加熱系統研製」,國立成功大學電機工程學系碩士論文,2006。
[15] 陳明坤、戴政祺,「半橋式串聯共振變流器於磁性奈米粒子熱療系統之應用」,生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2006。
[16] 陳建璋,「半橋串聯共振式磁奈米粒熱療加熱系統研製」,國立成功大學電機工程學系碩士論文,2007。
[17] 陳建璋、戴政祺,「半橋串聯共振式磁奈米粒熱療加熱系統研製」,生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2007。
[18] 陳建良、戴政祺,「變頻半橋感應式磁奈米粒熱療加熱系統」,生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2007。
[19] 陳建良,「變頻半橋感應式磁奈米粒熱療加熱系統」,國立成功大學電機工程學系碩士論文,2007。
[20] C. C. Chen, C. C. Tai, J. L. Chen, "The Design of an Applicator and Half-Bridge Series-Resonant Type Heating System for Magnetic Nanoparticle Thermotherapy," IEEE International Magnetics Conference, 2009.
[21] 陳俊成,「應用於奈米磁粒之半橋串聯諧振式雙頻耦合熱療加熱系統」,國立成功大學電機工程學系碩士論文,2008。
[22] 蘇信華,「奈米磁粒熱療感應加熱系統之研製」,國立成功大學電機工程學系碩士論文,2008。
[23] 蘇信華、戴政祺,「磁奈米粒熱療感應加熱系統之研製」,生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2008。
[24] 孔維彬,「以有限元素分析法作感應加熱線圈分析」,國立成功大學電機工程學系碩士論文,2008。
[25] 林子翔,「奈米粒熱療加熱系統之中低頻磁場聚焦探頭設計」,國立成功大學電機工程學系碩士論文, 2009。
[26] 徐彬翔,「高頻感應加熱器之DSP數位控制設計」,國立成功大學電機工程學系碩士論文,2011。
[27] 陳勁克,「以DSP建構數位監控系統於腫瘤電磁熱療系統」,國立成功大學電機工程學系碩士論文, 2011。
[28] 曾名弘,「奈米粒熱療加熱系統之模擬與探頭模型分析」,國立成功大學電機工程學系碩士論文, 2011。
[29] 徐彬翔、戴政祺、吳明璋,「高頻感應加熱器之DSP數位控制設計」,生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2011。
[30] 陳勁克、戴政祺、游本傳,「以DSP建構數位監控系統於腫瘤電磁熱療加熱器」, 生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2011。
[31] 曾名弘、戴政祺、陳仰豪、曾子庭,「奈米粒熱療加熱系統之模擬與探頭模型分析」,生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2011。
[32] 吳明璋,「大功率電磁熱療系統之數位回授溫度控制」,國立成功大學電機工程學系碩士論文,2012。
[33] 游本傳,「15-kW數位控制式高週波加熱系統之自動頻率追蹤」,國立成功大學電機工程學系碩士論文,2012。
[34] 曾子庭,「電磁熱療系統之即時數位電流回授控制」,國立成功大學電機工程學系碩士論文,2012。
[35] 陳仰豪,「多頻段感應加熱系統設計與大電流感測應用」,國立成功大學電機工程學系碩士論文,2012。
[36] 吳宗勳,「高功率感應加熱系統之數位溫度回授控制電路設計與腫瘤熱療應用」,國立成功大學電機工程學系碩士論文,2013。
[37] S. C. Huang, Y. Y. Chang, Y. J. Chao, Y. S. Shan, X. Z. Lin, and G. B. Lee, "Dual-Row Needle Arrays Under an Electromagnetic Thermotherapy System for Bloodless Liver Resection Surgery," IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, VOL. 59, NO. 3, MARCH 2012.
[38] R. Zuchini, C. H. Huang, H. W. Tsai, S. C. Huang, C. P. Lin, C. Y. Chen, G. B. Lee, and X. Z. Lin, "Electromagnetic Thermoablation to treat thrombocytopenia in cirrhotic and hypersplenic rates," Journal of gastroenterology Hepatology, Vol. 25, pp. 1578-1586, 2010.
[39] Y. J. Chao, Y. S. Shan, R. Zuchini, H. W. Tsai, P. W. Lin, G. B. Lee, and X. Z. Lin, "Successfully seal pancreatic end after thermal distal pancreatectomy using needle arrays in alternating electromagnetic fields," Surg. Innov., Vol. 20, No. 2, pp. 150-157, Apr. 2013.
[40] X.Z. Lin, R. Zuchini, H.W. Tsai, C.Y. Chen, C.H. Huang, S.C. Huang et al. "Electromagnetic thermotherapy using fine needles for hepatoma treatment," European Journal of Surgical Oncolog, Vol. 37, pp. 604-610, 2011.
[41] C. J. Lo, C. Y. Chen, H. W. Tsai, R. Zuchini, G. B. Lee, and X. Z. Lin, "Partial splenectomy using an electromagnetic thermal surgery system in a porcine model," Int. J. Hyperthermia, Vol. 27, No. 2, pp. 108-115, Mar. 2011.
[42] S. C. Huang, J. W. Kang, H. W. Tsai, Y. S. Shan, X. Z. Lin, and G. B. Lee, "Electromagnetic Thermotherapy System With Needle Arrays: A Practical Tool for the Removal of Cancerous Tumors," IEEE Transactions on Biomedical Engineering, Vol. 61, No. 2, pp. 598-605, February 2014.
[43] C. F. Huang, X. Z. Lin, and W. H. Lo, "Design and Construction of a Hyperthermia System with Improved Interaction of Magnetic Induction-Heating," 32nd Annual International Conference of the IEEE EMBS Buenos Aires, Argentina, August 31 - September 4, 2010.
[44] L. A. Zadeh, "Fuzzy Sets*," Information And Control, Vol. 8, 338-353(1965).
[45] Y. Wang, F. Cao, "Induction Heating Power Supply Temperature Control Based on a Novel Fuzzy Controller," International Conference on Computer and Electrical Engineering 2008.
[46] Y. Wang, "Study of Induction Heating Power Supply Based on Fuzzy Controller," Industrial Electronics and Applications, 2009.
[47] C. Cheng, "Design of Fuzzy Controller for Induction Heating Using DSP," in Proc. 5th Conf. on Ind. Elec. and App., pp. 2276-2280, 2010.
[48] N. Mohan, T. M. Undeland, and W. P. Robbins, "Power Electronics: Converters, Applications, and Design," John Wiley & Sons,Inc, 1995.
[49] G. M. Segura, "Induction Heating Converter's Design, Control and Modeling Applied to Continuous Wire Heating," Doctoral Thesis, universitat politecnica de catalunya(upc) , 2012.
[50] 梁適安,「交換式電源供給器之理論與實務設計」,全華出版社,2008。
[51] C. C. Lee, "Fuzzy logic in control systems: Fuzzy logic controller, part I," IEEE Trans. Syst., Man, Cybern., Vol. 20, No. 2, pp. 404-418, 1990.
[52] C. C. Lee, "Fuzzy logic in control systems: Fuzzy logic controller, part II," IEEE Trans. Syst., Man, Cybern., Vol. 20, No. 2, pp. 419-435, 1990.
[53] F. Betin, A. Sivert, A. Yazidi, and G. A. Capolino, "Determination of Scaling Factors for Fuzzy Logic Control Using the Sliding-Mode Approach Application to Control of a DC Machine Drive," IEEE Transactions on Industrial Electronics, Vol. 54, No. 1, pp. 296-309, February 2007.
[54] Y. Chen, C. Perng, "Input Scaling Factors in Fuzzy Control Systems," Third IEEE Inter. Conf. on Fuzzy Syst., June 1994.
[55] Y. J. Yoon, Y. J. Lee, T. H. Won, C. S. Kim, and M. H. Lee, "A Study on Design of Fuzzy Logic Controller Using Adaptive Scaling Factor," IEEE International Symposium on Industrial Electronics, Vol. 1, pp. 320-325, 2002.
[56] J. Victor and A. Dourado, "Adaptive scaling factors algorithm for the fuzzy logic controller," presented at the 6th IEEE Int. Conf. Fuzzy Syst., Barcelona, Spain, 1997.
[57] S. Franco, "Design With Operational Amplifiers And Analog Integrated Circuits Third Edition," Mc Graw Hill, 2002.
[58] "Micropower Thermocouple Cold Junction Compensator LT1025 Data Manual," Linear Technology.
[59] 葉倍宏,「Visual Basic 程式設計」,全華出版社,2010。
[60] 陳立元、范逸之、廖錦棋,「Visual Basic 2010 與自動化系統監控-RS232串列通訊篇」,松崗出版社,2012。
[61] H. Rhim, S. N. Goldberg, G. D. Dodd 3rd, et al, "Essential Techniques for Successful Radio-Frequency Thermal Ablation of Malignant Hepatic Tumors," RadioGraphics 2001, 21:S17–S35.
[62] D. Haemmerich, S. Tungjitkusolmun, S. T. Staelin, F. T. Lee Jr, D. M. Mahvi, J. G. Webster, "Finite-Element Analysis of Hepatic Multiple Probe Radio-Frequency Ablation," IEEE Trans Biomed, Vol. 49, No.7, pp. 836-842, July 2002.
[63] "Introduction: PID Controller Design," Carnegie Mellon University PID Tutorial.
[64] "Fuzzy Logic Toolbox," MathWorks.
[65] W. Q. Lindh, M. Pooler, C. D. Tamparo, B. M. Dahl, "Delmar's Comprehensive Medical Assisting: Administrative and Clinical Competencies," Cengage Learning, pp. 573, 9 March 2009.
論文全文使用權限
  • 同意授權校內瀏覽/列印電子全文服務,於2019-07-18起公開。
  • 同意授權校外瀏覽/列印電子全文服務,於2019-07-18起公開。


  • 如您有疑問,請聯絡圖書館
    聯絡電話:(06)2757575#65773
    聯絡E-mail:etds@email.ncku.edu.tw