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系統識別號 U0026-0802201809562400
論文名稱(中文) 印尼心臟衰竭病人之症狀負荷與生活品質
論文名稱(英文) Symptom Burden and Health-Related Quality of Life Among Patients with Heart Failure in Indonesia
校院名稱 成功大學
系所名稱(中) 護理學系
系所名稱(英) Department of Nursing
學年度 106
學期 1
出版年 107
研究生(中文) 陳政彬
研究生(英文) Masroni
學號 T26057014
學位類別 碩士
語文別 英文
論文頁數 119頁
口試委員 召集委員-王榮德
口試委員-周承珍
指導教授-陳幸眉
中文關鍵字 None 
英文關鍵字 Heart failure  symptom burden  health-related quality of life 
學科別分類
中文摘要 None
英文摘要 Symptom Burden and Health-Related Quality of Life Among Patients with Heart Failure in Indonesia

ABSTRACT

Background: Heart Failure (HF) is a complex syndrome that can cause a variety of symptoms and multiple organ dysfunctions, leading to a greater symptom burden than other chronic diseases. Symptom burden in patients with HF may affect functional status, survival, and economic outcomes, and contribute to poor health-related quality of life (HRQOL) of the patients.
Purpose: This cross-sectional study examine of the relationship between symptom burden and HRQOL among patients with HF in Indonesia.
Method: A convenience sample of 164 heart failure patients was recruited from a cardiology outpatient department, inpatients cardiac ward, and echocardiography room at a public hospital in Indonesia. A set of self-reported questionnaires was used to including the demographic questionnaire, the Memorial Symptom Assessment Scale-Heart Failure (MSAS-HF), the World Health Organization Quality of Life (WHOQOL)-BREF and the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Descriptive statistics, bivariate analyses (independent t-tests, one-way ANOVA, and Pearson correlation), and hierarchical regression analysis were utilized to analyse the data.
Results: The mean age of the participants was 58.37 years old, the mean duration of HF diagnosis was 42.59 months, and the mean frequency of admission was 2.18 times. All participants experienced a mean of 9.72 ± 5.44 symptoms, while chest pain and lack of energy were the most prevalent. The most burdensome symptoms were chest pain, lack of energy, difficulty sleeping, numbness/tingling in hands/feet and cough. A hierarchical multiple regression analysis showed that after controlling for demographic factors and illness-related factors, higher NYHA classes, psychological symptoms and heart failure symptoms predicted 55.1% of the variance in HRQOL by MLHFQ measurement. In terms of predictors of WHOQOL-BREF domains, participants who had CAD and DM type 2 comorbidity, higher NYHA classes, and higher psychological symptoms predicted 35.7% of the variance on physical domain, participants who had CAD comorbidity and psychological symptoms predicted 31.4% of the variance on psychological domain, participants who had CAD comorbidity, high number of medication use and higher heart failure symptoms predicted 29.5% of the variance on social relationship domain, while lower income level and had CAD comorbidity predicted 40.7% of the variance on environment domain, and whereas longer duration of HF diagnosis, had CAD comorbidity, diuretics medication use, and higher heart failure symptom predicted 11.8% of the variance on overall QoL domain, in HRQOL by WHOQOL-BREF measurement, respectively.
Conclusion: The study found that symptom burden has a great impact on quality of life. The consistency of the finding on NYHA classes and CAD comorbidity as major predictors in the two measurements of HRQOL across every model for the domains is impressive. This suggests that CAD comorbidity and NYHA classes are essential for patients with heart failure experiences decreased HRQOL. Future interventions directed to make the condition of patients with HF more stable and decrease the prevalence of the symptoms in order to improve HRQOL.

Keywords
Heart failure, symptom burden, health-related quality of life
論文目次 ABSTRACT I
ACKNOWLEDGEMENTS II
TABLE OF CONTENTS III
LIST OF TABLES VI
LIST OF FIGURES VI
CHAPTER I INTRODUCTION 1
1.1. Background 1
1.2. Significance of the Study 2
1.3. Research Purpose 4
1.4. Conceptual Framework 5
1.5. Definition of Terms 5
CHAPTER II LITERATURE REVIEW 7
2.1. Overview of Heart Failure 7
2.1.1. Etiology of Heart Failure 7
2.1.2. Classification of Heart Failure 8
2.1.3. Symptoms and Signs of Heart Failure 9
2.1.4. Summary 10
2.2. Symptom Burden 10
2.3. Factors Associated with Symptom Burden 12
2.4. Quality of Life (QoL) 13
2.5. Health-Related Quality of Life (HRQOL) 14
2.6. Quality of Life and Health Related Quality of Life in Patients with Heart Failure 14
2.7. Factor Associated with HRQOL in Patients with HF 15
2.7.1. Demographic Factors 15
2.7.2. Illness-Related Factors of HF and HRQOL 16
2.8. Relationship Between Symptom Burden and HRQOL Among Patients with HF 17
2.8.1. Summary 18
CHAPTER III METHODS 19
3.1 Research Design 19
3.2 Sample and Setting 19
3.3 Instruments 20
3.3.1. Demographic and Illness-related Factors Questionnaire 20
3.3.2. Symptoms Burden 21
3.3.3. HRQOL 22
3.4 Procedures 25
3.5 Ethics and Protection of Human Subjects 27
3.6 Data Analysis 27
3.7 Summary 29
CHAPTER IV RESULT 30
4.1. Demographic Data and Illness-Related Factors of the Participants 30
4.2. Symptom Burden and Health-Related Quality of Life 32
4.2.1. Symptom Burden 32
4.2.2. MLHFQ 34
4.2.3. WHOQOL-BREF 35
4.3. Relationship Between Demographic, Illness-Related Factors, Symptom Burden and Health-Related Quality of Life 36
4.3.1. MLHFQ 36
4.3.2. WHOQOL-BREF 37
4.4. Predictors of Health-Related Quality of Life 41
4.4.1. MLHFQ 41
4.4.2. WHOQOL-BREF 42
CHAPTER V DISCUSSION 47
5.1. Participants Description 47
5.1.1. Demographic Data 47
5.1.2. Illness-related Factors 49
5.2. Symptom Burden 51
5.3. Health-Related Quality of Life 52
5.3.1. MLHFQ 52
5.3.2. WHOQOL-BREF 54
5.4. Predictors of Health-Related Quality of Life 55
5.4.1. MLHFQ 55
5.4.2. WHOQOL-BREF 57
5.6. Conclusion 58
REFERENCES 60
APPENDICES 70
Appendix 1 70
Appendix 2 71
Appendix 3 73
Appendix 4 74
Appendix 5 77
Appendix 6 80
Appendix 7 89
Appendix 8 98
Appendix 9 113
Appendix 10 116
參考文獻 REFERENCES
Aburuz, M. E., Alaloul, F., Saifan, A., Masadeh, R., & Abusalem, S. (2016). Quality of life for Saudi patients with heart failure: A cross-sectional correlational study. Global Journal of Health Science,8(3), 49-58. doi:10.5539/gjhs.v8n3p49
America, H. F. (2010). Executive Summary: HFSA 2010 comprehensive heart failure practice guideline. Journal of Cardiac Failure,16(6), 475-539. doi:10.1016/j.cardfail.2010.04.005
America, H. F. (2010). Section 2: Conceptualization and working definition of heart failure. Journal of Cardiac Failure,16(6), e34-e37. doi:10.1016/j.cardfail.2010.05.011
American Heart Association (AHA). Classes of heart failure. website. http://www.heart.org/HEARTORG/Conditions/HeartFailure/AboutHeartFailure/Classes-of-Heart-Failure_UCM_306328_Article.jsp#.V56_BuCyTIU. Accessed August 01, 2016.
Aranda, J. M., Johnson, J. W., & Conti, J. B. (2009). Current trends in heart failure readmission rates: analysis of medicare data. Clinical Cardiology,32(1), 47-52. doi:10.1002/clc.20453
Armstrong, T. S. (2003). Symptoms experience: A concept analysis. Oncology Nursing Forum,30(4), 601-606. doi:10.1188/03.onf.601-606
Ather, S., Chan, W., Bozkurt, B., Aguilar, D., Ramasubbu, K., Zachariah, A. A., . . . Deswal, A. (2012). Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction. Journal of the American College of Cardiology,59(11), 998-1005. doi:10.1016/j.jacc.2011.11.040
Bayliss, E. A., Ellis, J. L., & Steiner, J. F. (2007). Barriers to self-management and quality-of-life outcomes in seniors with multimorbidities. The Annals of Family Medicine,5(5), 395-402. doi:10.1370/afm.722
Beaton, D. E., Bombardier, C., Guillemin, F., & Ferraz, M. B. (2000). Guidelines for the process of cross-cultural adaptation of self-report measures. Spine,25(24), 3186-3191. doi:10.1097/00007632-200012150-00014
Behlouli, H., Feldman, D., Ducharme, A., Frenette, M., Giannetti, N., Grondin, F., . . . Pilote, L. (2009). Identifying relative cut-off scores with neural networks for interpretation of the minnesota living with heart failure questionnaire. 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society. doi:10.1109/iembs.2009.5334659
Bekelman, D. B., Havranek, E. P., Becker, D. M., Kutner, J. S., Peterson, P. N., Wittstein, I. S., ... & Dy, S. M. (2007). Symptoms, depression, and quality of life in patients with heart failure. Journal of Cardiac Failure, 13(8), 643-648.
Bekelman, D. B., Parry, C., Curlin, F. A., Yamashita, T. E., Fairclough, D. L., & Wamboldt, F. S. (2010). A comparison of two spirituality instruments and their relationship with depression and quality of life in chronic heart failure. Journal of Pain and Symptom Management,39(3), 515-526. doi:10.1016/j.jpainsymman.2009.08.005
Bekelman, D. B., Rumsfeld, J. S., Havranek, E. P., Yamashita, T. E., Hutt, E., Gottlieb, S. H., . . . Kutner, J. S. (2009). Symptom burden, depression, and spiritual well-being: A comparison of heart failure and advanced cancer patients. Journal of General Internal Medicine,24(5), 592-598. doi:10.1007/s11606-009-0931-y
Binaei, N., Moeini, M., Sadeghi, M., Najafi, M., & Mohagheghian, Z. (2016). Effects of hope promoting interventions based on religious beliefs on quality of life of patients with congestive heart failure and their families. Iranian Journal of Nursing and Midwifery Research,21(1), 77. doi:10.4103/1735-9066.174755
Blinderman, C. D., Homel, P., Billings, J. A., Portenoy, R. K., & Tennstedt, S. L. (2008). Symptom distress and quality of life in patients with advanced congestive heart failure. Journal of Pain and Symptom Management,35(6), 594-603. doi:10.1016/j.jpainsymman.2007.06.007
Burt, C. W., & Schappert, S. M. (2004). Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 1999--2000. Vital and Health Statistics. 13 (157), 1-70.
Callender, T., Woodward, M., Roth, G., Farzadfar, F., Lemarie, J.-C., Gicquel, S., . . . Byass, P. (2014). Heart failure care in low- and middle-income countries: A systematic review and meta-analysis. Plos Medicine, 11(8), e1001699.
Calvert, M. J., Freemantle, N., & Cleland, J. G. (2005). The impact of chronic heart failure on health-related quality of life data acquired in the baseline phase of the CARE-HF study. European Journal of Heart Failure,7(2), 243-251. doi:10.1016/j.ejheart.2005.01.012
Carlson, B., Pozehl, B., Hertzog, M., Zimmerman, L., & Riegel, B. (2013). Predictors of overall perceived health in patients with heart failure. The Journal of Cardiovascular Nursing,28(3), 206-215. doi:10.1097/jcn.0b013e31824987a8
Carlson, B., Pozehl, B., Hertzog, M., Zimmerman, L., & Riegel, B. (2013). Predictors of overall perceived health in patients with heart failure. The Journal of Cardiovascular Nursing,28(3), 206-215. doi:10.1097/jcn.0b013e31824987a8
Casida, J. M., & Parker, J. (2012). A preliminary investigation of symptom pattern and prevalence before and up to 6 months after implantation of a left ventricular assist device. Journal of Artificial Organs,15(2), 211-214. doi:10.1007/s10047-011-0622-4
Chen, H. M., Clark, A. P., Tsai, L. M., Liu, Y., Wu, L. M., & Wu, S. J. (2013). Excessive daytime sleepiness in taiwanese people with heart failure. Journal of Nursing Research, 21(1), 39-48. doi:10.1097/jnr.0b013e3182828f2f
Chung, M. L., Moser, D. K., Lennie, T. A., & Frazier, S. K. (2013). Perceived social support predicted quality of life in patients with heart failure, but the effect is mediated by depressive symptoms. Quality of Life Research,22(7), 1555-1563. doi:10.1007/s11136-012-0294-4
Clark, A. P., & Mcdougall, G. (2006). Cognitive impairment in heart failure. Dimensions of Critical Care Nursing,25(3), 93-100. doi:10.1097/00003465-200605000-00001
Clark, D. O., Tu, W., Weiner, M., & Murray, M. D. (2003). Correlates of health-related quality of life among lower-income, urban adults with congestive heart failure. Heart & Lung: The Journal of Acute and Critical Care,32(6), 391-401. doi:10.1016/j.hrtlng.2003.07.005
Cleeland, C. S. (2007). Symptom burden: Multiple symptoms and their impact as patient-reported outcomes. JNCI Monographs,2007(37), 16-21. doi:10.1093/jncimonographs/lgm005
Coelho, R., Ramos, S., Prata, J., Bettencourt, P., Ferreira, A., & Cerqueira-Gomes, M. (2005). Heart failure and health related quality of life. Clinical Practice and Epidemiology in Mental Health, 1(1), 19.
Comín Colet, J., Anguita, M., Formiga, F., Almenar, L., Crespo Leiro, M., Manzano, L., . . . Enjuanes, C. (2016). Health-related quality of life of patients with chronic systolic heart failure in Spain: Results of the VIDA-IC study. Revista Española de Cardiología, 69(3), 256-271.
Corvera-Tindel, T., Doering, L. V., Roper, J., & Dracup, K. (2009). Emotional functioning drives quality of life in men with heart failure. Progress in Cardiovascular Nursing,24(1), 2-11. doi:10.1111/j.1751-7117.2009.00026.x
Cowie, M. R., Wood, D. A., Coats, A. J., Thompson, S. G., Poole Wilson, P. A., Suresh, V., & Sutton, G. C. (1999). Incidence and aetiology of heart failure; A population-based study. European Heart Journal,20(6), 421-428. doi:10.1053/euhj.1998.1280
Daniels, L. B., Clopton, P., Bhalla, V., Krishnaswamy, P., Nowak, R. M., Mccord, J., . . . Maisel, A. S. (2006). How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. American Heart Journal,151(5), 999-1005. doi:10.1016/j.ahj.2005.10.011
Dehkordi, A. H., & Far, A. K. (2015). Effect of exercise training on the quality of life and echocardiography parameter of systolic function in patients with chronic heart failure: A randomized trial. Asian Journal of Sports Medicine,6(1). doi:10.5812/asjsm.22643
Dekker, R. L., Lennie, T. A., Doering, L. V., Chung, M. L., Wu, J., & Moser, D. K. (2014). Coexisting anxiety and depressive symptoms in patients with heart failure. European Journal of Cardiovascular Nursing,13(2), 168-176. doi:10.1177/1474515113519520
Demir, M., & Unsar, S. (2011). Assessment of quality of life and activities of daily living in Turkish patients with heart failure. International Journal of Nursing Practice,17(6), 607-614. doi:10.1111/j.1440-172x.2011.01980.x
Deurenberg, P., Deurenberg-Yap, M., & Guricci, S. (2002). Asians are different from Caucasians and from each other in their body mass index/body fat per cent relationship. Obesity Reviews, 3(3), 141-146. doi:10.1046/j.1467-789X.2002.00065.x
Doorslaer, E. V., Odonnell, O., Rannan-Eliya, R. P., Somanathan, A., Adhikari, S. R., Garg, C. C., . . . Zhao, Y. (2006). Effect of payments for health care on poverty estimates in 11 countries in Asia: an analysis of household survey data. The Lancet,368(9544), 1357-1364. doi:10.1016/s0140-6736(06)69560-3
Dunderdale, K., Thompson, D. R., Miles, J. N., Beer, S. F., & Furze, G. (2005). Quality-of-life measurement in chronic heart failure: Do we take account of the patient perspective? European Journal of Heart Failure,7(4), 572-582. doi:10.1016/j.ejheart.2004.06.006
Erceg, P., Despotovic, N., Milosevic, D. P., Soldatovic, I., Zdravkovic, S., Tomic, S., ... & Potic, B. (2013). Health-related quality of life in elderly patients hospitalized with chronic heart failure. Clinical Interventions in Aging, 8, 1539.
Faller, H., Störk, S., Schuler, M., Schowalter, M., Steinbüchel, T., Ertl, G., & Angermann, C. E. (2009). Depression and disease severity as predictors of health-related quality of life in patients with chronic heart failure—A structural equation modeling approach. Journal of Cardiac Failure,15(4), 286-292. doi:10.1016/j.cardfail.2008.10.022
Faul, F., Erdfelder, E., Buchner, A., & Lang, A. (2009). Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses. Behavior Research Methods,41(4), 1149-1160. doi:10.3758/brm.41.4.1149
Fayers, P. M., & Machin, D. (2013). Quality of life: The assessment, analysis and interpretation of patient-reported outcomes. John Wiley & Sons.
Ferrans, C. E. (2005). Definitions and conceptual models of quality of life. Outcomes Assessment in Cancer,14-30. doi:10.1017/cbo9780511545856.002
Flegal, K. M., Carroll, M. D., Ogden, C. L., & Curtin, L. R. (2010). Prevalence and trends in obesity among US adults, 1999-2008. Jama,303(3), 235-241. doi:10.1001/jama.2009.2014
Fotos, N. V., Giakoumidakis, K., Kollia, Z., Galanis, P., Copanitsanou, P., Pananoudaki, E., & Brokalaki, H. (2013). Health-related quality of life of patients with severe heart failure. A cross-sectional multicentre study. Scandinavian Journal of Caring Sciences,27(3), 686-694. doi:10.1111/j.1471-6712.2012.01078.x
Gapstur, R. L. (2007). Symptom Burden: A concept analysis and implications for oncology nurses. Oncology Nursing Forum,34(3), 673-680. doi:10.1188/07.onf.673-680
Gheorghiade, M., Vaduganathan, M., Fonarow, G. C., & Bonow, R. O. (2013). Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology, 61(4), 391-403.
Go, A., Mozaffarian, D., Roger, V., Benjamin, E., Berry, J., Borden, W., . . . Turner, M. (2013). Heart disease and stroke statistics--2013 update: A report from the American Heart Association. Circulation, 127(1), e6-e245
Goodell, T. T., & Nail, L. M. (2005). Operationalizing symptom distress in adults with cancer: A literature synthesis. Oncology Nursing Forum,32(2). doi:10.1188/05.onf.e42-e47
Goodman, H., Firouzi, A., Banya, W., Lau-Walker, M., & Cowie, M. R. (2013). Illness perception, self-care behaviour and quality of life of heart failure patients: A longitudinal questionnaire survey. International Journal of Nursing Studies,50(7), 945-953. doi:10.1016/j.ijnurstu.2012.11.007
Hägglund, L., Boman, K., Olofsson, M., & Brulin, C. (2007). Fatigue and health-related quality of life in elderly patients with and without heart failure in primary healthcare. European Journal of Cardiovascular Nursing,6(3), 208-215. doi:10.1016/j.ejcnurse.2006.09.004
Haider, A. W., Larson, M. G., Franklin, S. S., & Levy, D. (2003). Systolic blood pressure, diastolic blood pressure, and pulse pressure as predictors of risk for congestive heart failure in the Framingham heart study. Annals of Internal Medicine,138(1), 10-16. doi:10.7326/0003-4819-138-1-200301070-00006
Hefner, R. W. (2016). Indonesia, Islam, and the new U.S. administration. The Review of Faith & International Affairs, 14(2), 59-66. doi:10.1080/15570274.2016.1184444
Heidenreich, P. A., Albert, N. M., Allen, L. A., Bluemke, D. A., Butler, J., Fonarow, G. C., . . . Trogdon, J. G. (2013). Forecasting the impact of heart failure in the United States: A policy statement from the American Heart Association. Circulation: Heart Failure,6(3), 606-619. doi:10.1161/hhf.0b013e318291329a
Heo, S. (2008). Predictors and effect of physical symptom status on health-related quality of life in patients with heart failure. American Journal of Critical Care, 17(2), 124.
Heo, S., Lennie, T. A., Okoli, C., & Moser, D. K. (2009). Quality of life in patients with heart failure: Ask the patients. Heart & Lung: The Journal of Acute and Critical Care,38(2), 100-108. doi:10.1016/j.hrtlng.2008.04.002
Heo, S., Moser, D. K., Pressler, S. J., Dunbar, S. B., Mudd-Martin, G., & Lennie, T. A. (2015). Psychometric properties of the symptom status questionnaire–heart failure. The Journal of Cardiovascular Nursing,30(2), 136-144. doi:10.1097/jcn.0000000000000102
Heo, S., Moser, D., Chung, M., & Lennie, T. (2012). Social status, health-related quality of life, and event-free survival in patients with heart failure. European Journal of Cardiovascular Nursing, 11(2), 141-149.
Ho, C., Clochesy, J. M., Madigan, E., & Liu, C. (2007). Psychometric evaluation of the chinese version of the minnesota living with heart failure questionnaire. Nursing Research,56(6), 441-448. doi:10.1097/01.nnr.0000299849.21935.c4
Hu, X., Hu, X., Su, Y., & Qu, M. (2016). Quality of life among primary family caregivers of patients with heart failure in Southwest China. Rehabilitation Nursing, 1. doi:10.1002/rnj.290
Huang, T., Moser, D. K., Hwang, S., Lennie, T. A., Chung, M., & Heo, S. (2010). Comparison of health-related quality of life between American and Taiwanese heart failure patients. Journal of Transcultural Nursing,21(3), 212-219. doi:10.1177/1043659609358779
Hunt, S., et al. (2001). "ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary." Journal of the American College of Cardiology 38(7), 2101-2113.
Hwang, S. L., Liao, W. C., & Huang, T. Y. (2014). Predictors of quality of life in patients with heart failure. Japan Journal of Nursing Science, 11(4), 290-298.
Iqbal, J., Francis, L., Reid, J., Murray, S., & Denvir, M. (2010). Quality of life in patients with chronic heart failure and their carers: a 3-year follow-up study assessing hospitalization and mortality. European Journal of Heart Failure,12(9), 1002-1008. doi:10.1093/eurjhf/hfq114
Johansson, P., Dahlström, U., & Broström, A. (2006). Factors and interventions influencing health-related quality of life in patients with heart failure: A review of the literature. European Journal of Cardiovascular Nursing,5(1), 5-15. doi:10.1016/j.ejcnurse.2005.04.011
Jones, J., Mcdermott, C. M., Nowels, C. T., Matlock, D. D., & Bekelman, D. B. (2012). The experience of fatigue as a distressing symptom of heart failure. Heart & Lung: The Journal of Acute and Critical Care,41(5), 484-491. doi:10.1016/j.hrtlng.2012.04.004
Juenger, J., Schellberg, D., Kraemer, S., Haunstetter, A., Zugck, C., Herzog, W., & Haass, M. (2002). Health related quality of life in patients with congestive heart failure: Comparison with other chronic diseases and relation to functional variables. Heart, 87(3), 235-241. doi:10.1136/heart.87.3.235
Kato, M., Stevenson, L. W., Palardy, M., Campbell, P. M., May, C. W., Lakdawala, N. K., . . . Setoguchi, S. (2012). The worst symptom as defined by patients during heart failure hospitalization: Implications for response to therapy. Journal of Cardiac Failure,18(7), 524-533. doi:10.1016/j.cardfail.2012.04.012
Kawecka-Jaszcz, K., Klocek, M., Tobiasz-Adamczyk, B., & Bulpitt, C. J. (2013). Health-related quality of life in cardiovascular patients. Springer Milan.
Kim, H. (2013). Statistical notes for clinical researchers: Assessing normal distribution (2) using skewness and kurtosis. Restorative Dentistry & Endodontics,38(1), 52-54. doi:10.5395/rde.2013.38.1.52
Kim, H. M., Kim, J., & Hwang, S. Y. (2015). Health-related quality of life in symptomatic postmyocardial infarction patients with left ventricular dysfunction. Asian Nursing Research,9(1), 47-52. doi:10.1016/j.anr.2014.11.004
Kozhekenova, L. (2014). Impact of comorbidities on health-related quality of life among heart failure patients in Kazakhstan. Biology and Medicine, 6(1), 1.
Kutner, J. S., Kassner, C. T., & Nowels, D. E. (2001). Symptom burden at the end of life: Hospice providers' perceptions. Journal of Pain and Symptom Management, 21(6), 473-480.
Lackey, N.R., &Wingate, A.L. (1998). The pilot study: One key to research success. Advanced design in nursing research (2nd ed.). Thousand Oaks, CA: Sage.
Lee, C. S., & Auld, J. (2015). Heart failure: A primer. Critical Care Nursing Clinics of North America, 27(4), 413-425.
Lee, C. S., Chien, C. V., Bidwell, J. T., Gelow, J. M., Denfeld, Q. E., Creber, R. M., . . . Mudd, J. O. (2014). Comorbidity profiles and inpatient outcomes during hospitalization for heart failure: An analysis of the U.S. Nationwide inpatient sample. BMC Cardiovascular Disorders, 14(1). doi:10.1186/1471-2261-14-73.
Lee, J. O., & Song, R. (2015). Symptom Management to predict quality of life in patients with heart failure: A structural equation modeling approach. Journal of Korean Academy of Nursing,45(6), 846-856. doi:10.4040/jkan.2015.45.6.846
Lee, K. S., Lennie, T. A., Dunbar, S. B., Pressler, S. J., Heo, S., Song, E. K., . . . Moser, D. K. (2015). The association between regular symptom monitoring and self-care management in patients with heart failure. The Journal of Cardiovascular Nursing,30(2), 145-151. doi:10.1097/jcn.0000000000000128
Lewis, E. F., Johnson, P. A., Johnson, W., Collins, C., Griffin, L., & Stevenson, L. W. (2001). Preferences for quality of life or survival expressed by patients with heart failure. The Journal of Heart and Lung Transplantation,20(9), 1016-1024. doi:10.1016/s1053-2498(01)00298-4
Lipscomb, J., Gotay, C. C., & Snyder, C. (Eds.). (2004). Outcomes assessment in cancer: measures, methods and applications. Cambridge University Press.
Louredo, A. B., Leite, A. L., Salerno, G. R., Fernandes, M., & Blascovi-Assis, S. (2015). Instruments to assess quality of life in patients with heart failure. Fisioterapia em Movimento,28(4), 851-858. doi:10.1590/0103-5150.028.004.ar03
Lum, H. D., Carey, E. P., Fairclough, D., Plomondon, M. E., Hutt, E., Rumsfeld, J. S., & Bekelman, D. B. (2016). Burdensome physical and depressive symptoms predict heart failure–specific health status over one year. Journal of Pain and Symptom Management, 51(6), 963-970. doi:10.1016/j.jpainsymman.2015.12.328
Ministry of Health Indonesia. (2014). Situasi kesehatan jantung. Jakarta, Indonesia.
Moser, D. K., Doering, L. V., & Chung, M. L. (2005). Vulnerabilities of patients recovering from an exacerbation of chronic heart failure. American Heart Journal,150(5) 984-e7. doi:10.1016/j.ahj.2005.07.028
Moser, D. K., Dracup, K., Evangelista, L. S., Zambroski, C. H., Lennie, T. A., Chung, M. L., . . . Heo, S. (2010). Comparison of prevalence of symptoms of depression, anxiety, and hostility in elderly patients with heart failure, myocardial infarction, and a coronary artery bypass graft. Heart & Lung: The Journal of Acute and Critical Care,39(5), 378-385. doi:10.1016/j.hrtlng.2009.10.017
Moser, D. K., Yamokoski, L., Sun, J. L., Conway, G. A., Hartman, K. A., Graziano, J. A., . . . Stevenson, L. W. (2009). Improvement in health-related quality of life after hospitalization predicts event-free survival in patients with advanced heart failure. Journal of Cardiac Failure,15(9), 763-769. doi:10.1016/j.cardfail.2009.05.003
Mulligan, K., Mehta, P. A., Fteropoulli, T., Dubrey, S. W., Mcintyre, H. F., Mcdonagh, T. A., . . . Newman, S. (2012). Newly diagnosed heart failure: Change in quality of life, mood, and illness beliefs in the first 6 months after diagnosis. British Journal of Health Psychology,17(3), 447-462. doi:10.1111/j.2044-8287.2011.02047.x
Naghi, J. J., Philip, K. J., Phan, A., Cleenewerck, L., & Schwarz, E. R. (2012). The effects of spirituality and religion on outcomes in patients with chronic heart failure. Journal of Religion and Health,51(4), 1124-1136. doi:10.1007/s10943-010-9419-7
Negarandeh, R., Delkhosh, M., Janani, L., Samiei, N., & Ghasemi, E. (2015). The relationship between perceived life changes and mental health in family caregivers of patients with heart failure who referred to rajaei cardiovascular medical and research center, Tehran. International Journal of Community Based Nursing and Midwifery, 3(4), 283.
Norris, C. M., Ghali, W. A., Galbraith, P. D., Graham, M. M., Jensen, L. A., & Knudtson, M. L. (2004). Women with coronary artery disease report worse health-related quality of life outcomes compared to men. Health and quality of life outcomes, 2(1), 21.
O Ola, B. A., Adewuya, A. O., Ajayi, O. E., Akintomide, A. O., Oginni, O. O., & Ologun, Y. A. (2006). Relationship between depression and quality of life in Nigerian outpatients with heart failure. Journal of Psychosomatic Research,61(6), 797-800. doi:10.1016/j.jpsychores.2006.04.022
O’Connor, C. M., Whellan, D. J., Lee, K. L., Keteyian, S. J., Cooper, L. S., Ellis, S. J., . . . Investigators, F. T. (2009). Efficacy and safety of exercise training in patients with chronic heart failure. Jama,301(14), 1439-1450. doi:10.1001/jama.2009.454
Obiegło, M., Uchmanowicz, I., Wleklik, M., Jankowska-Polańska, B., & Kuśmierz, M. (2016). The effect of acceptance of illness on the quality of life in patients with chronic heart failure. European Journal of Cardiovascular Nursing,15(4), 241-247. doi:10.1177/1474515114564929
Oudejans, I., Mosterd, A., Bloemen, J. A., Valk, M. J., Velzen, E. V., Wielders, J. P., . . . Hoes, A. W. (2011). Clinical evaluation of geriatric outpatients with suspected heart failure: Value of symptoms, signs, and additional tests. European Journal of Heart Failure,13(5), 518-527. doi:10.1093/eurjhf/hfr021
Padilla, G. V., Kagawa-Singer, M., & Ashing-Giwa, T. (2012). Quality of life, health and culture. Quality of life from nursing and patient perspectives, 105-135.
Papadopoulou, E. F., Mavrogeni, S. I., Dritsas, A., & Cokkinos, D. V. (2009). Assessment of quality of life using three activity questionnaires in heart failure patients after monthly, intermittent administration of levosimendan during a six-month period. Hellenic J Cardiol, 50(4), 269-274.
Peduzzi, P., Concato, J., Kemper, E., Holford, T. R., & Feinstein, A. R. (1996). A simulation study of the number of events per variable in logistic regression analysis. Journal of Clinical Epidemiology,49(12), 1373-1379. doi:10.1016/s0895-4356(96)00236-3
Pelegrino, V. M., Dantas, R. A., Ciol, M. A., Clark, A. M., Rossi, L. A., & Simões, M. V. (2011). Health-related quality of life in Brazilian outpatients with Chagas and non-Chagas cardiomyopathy. Heart & Lung, 40(3), e25-e31. doi:10.1016/j.hrtlng.2010.05.052
Philbin, E. F., Dec, G., Jenkins, P. L., & Disalvo, T. G. (2001). Socioeconomic status as an independent risk factor for hospital readmission for heart failure. The American Journal of Cardiology,87(12), 1367-1371. doi:10.1016/s0002-9149(01)01554-5
Plichta, S. B., & Kelvin, E. (2013). Munro's statistical methods for health care research (6 ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins.
Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G., Coats, A. J., . . . Meer, P. V. (2016). 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC. European Heart Journal,37(27), 2129-2200. doi:10.1093/eurheartj/ehw128
Portenoy, R., Thaler, H., Kornblith, A., Lepore, J. M., Friedlander-Klar, H., Kiyasu, E., . . . Scher, H. (1994). The memorial symptom assessment scale: An instrument for the evaluation of symptom prevalence, characteristics and distress. European Journal of Cancer,30(9), 1326-1336. doi:10.1016/0959-8049(94)90182-1
Ramos, S., Prata, J., Bettencourt, P., Gonçalves, F. R., & Coelho, R. (2016). Depression predicts mortality and hospitalization in heart failure: A six-years follow-up study. Journal of Affective Disorders,201, 162-170. doi:10.1016/j.jad.2016.05.024
Ramsenthaler, C., Osborne, T. R., Gao, W., Siegert, R. J., Edmonds, P. M., Schey, S. A., & Higginson, I. J. (2016). The impact of disease-related symptoms and palliative care concerns on health-related quality of life in multiple myeloma: a multi-centre study. BMC Cancer,16(1), 427. doi:10.1186/s12885-016-2410-2
Rector, T. S. (2005). Overview of the Minnesota living with heart failure questionnaire. Retrieved June, 25, 2007.
Rector, T. S., & Cohn, J. N. (1992). Assessment of patient outcome with the Minnesota living with heart failure questionnaire: Reliability and validity during a randomized, double-blind, placebo-controlled trial of pimobendan. American Heart Journal,124(4), 1017-1025. doi:10.1016/0002-8703(92)90986-6
Reeves, G., Alhurani, A., Frazier, S., Watkins, J., Lennie, T., & Moser, D. (2015). The association of comorbid diabetes mellitus and symptoms of depression with all-cause mortality and cardiac rehospitalization in patients with heart failure. BMJ Open Diabetes Research & Care, 3(1), e000077-e000077. doi:10.1136/bmjdrc-2014-000077.
Remes, J., MlEttinen, H., Reunanen, A., & Pyörälä, K. (1991). Validity of clinical diagnosis of heart failure in primary health care. European Heart Journal, 12(3), 315-321.
Remme, W. J. and K. Swedberg (2001). "Guidelines for the diagnosis and treatment of chronic heart failure." European Heart Journal 22(17), 1527-1560.
Rodríguez-Artalejo, F., Guallar-Castillón, P., Pascual, C. R., Otero, C. M., Montes, A. O., García, A. N., ... & Herrera, M. C. (2005). Health-related quality of life as a predictor of hospital readmission and death among patients with heart failure. Archives of Internal Medicine, 165(11), 1274-1279.
Roger, V. L. (2004). Trends in heart failure incidence and survival in a community-based population. Jama,292(3), 344. doi:10.1001/jama.292.3.344
Rutten, F. H., Moons, K. G., Cramer, M. J. M., Grobbee, D. E., Zuithoff, N. P., & Hoes, A. W. (2005). Recognising heart failure in elderly patients with stable chronic obstructive pulmonary disease in primary care: cross sectional diagnostic study. BMJ,331(7529), 1379-0. doi:10.1136/bmj.38664.661181.55
Salim, O. C., Sudharma, N. I., Rina, K., Kusumaratna, R. K., & Hidayat, A. (2007). Validity and reliability of World Health Organization Quality of Life-BREF to assess the quality of life in the elderly. Univ Med, 26, 27-38.
Sarna, L., & Brecht, M. (1997). Dimensions of symptom distress in women with advanced lung cancer: A factor analysis. Heart & Lung: The Journal of Acute and Critical Care,26(1), 23-30. doi:10.1016/s0147-9563(97)90006-6
Sieck, S. (2012). The economics and reimbursement of congestive heart failure. Contemporary Cardiology Short Stay Management of Acute Heart Failure,9-32. doi:10.1007/978-1-61779-627-2_2
Silveira, M. J., Kabeto, M. U., & Langa, K. M. (2005). Net worth predicts symptom burden at the end of life. Journal of Palliative Medicine,8(4), 827-837. doi:10.1089/jpm.2005.8.827
Skevington, S. M. (1999). Measuring quality of life in Britain: introducing the WHOQOL-100. Journal of Psychosomatic Research, 47(5), 449-459.
Skevington, S. M., Lotfy, M., & O'Connell, K. A. (2004). The World Health Organization's WHOQOL-BREF quality of life assessment: Psychometric properties and results of the international field trial. A report from the WHOQOL group. Quality of Life Research, 13(2), 299-310. doi:10.1023/b:qure.0000018486.91360.00
Sloan, J. (2002). Asking the obvious questions regarding patient burden. Journal of Clinical Oncology,20(1), 4-6. doi:10.1200/jco.2002.20.1.4
Solomon, S. D., Anavekar, N., Skali, H., McMurray, J. J., Swedberg, K., Yusuf, S., ... Pfeffer, M. A. (2005). Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients. Circulation,112(24), 3738-3744. doi:10.1161/circulationaha.105.561423
Solomon, S. D., Dobson, J., Pocock, S., Skali, H., Mcmurray, J. J., Granger, C. B., . . . Pfeffer, M. A. (2007). Influence of nonfatal hospitalization for heart failure on subsequent mortality in patients with chronic heart failure. Circulation,116(13), 1482-1487. doi:10.1161/circulationaha.107.696906
Steptoe, A., Mohabir, A., Mahon, N. G., & McKenna, W. J. (2000). Health related quality of life and psychological wellbeing in patients with dilated cardiomyopathy. Heart,83(6), 645-650. doi:10.1136/heart.83.6.645
Swedberg, K., Cleland, J., Dargie, H., Drexler, H., Follath, F., Komajda, M., . . . Remme, W. (2005). Guidelines for the diagnosis and treatment of chronic heart failure: Executive summary (update 2005): The task force for the diagnosis and treatment of chronic heart failure of the European Society of Cardiology. European Heart Journal, 26(11), 1115-1140.
Tatukude, C., Rampengan, S. H., & Panda, A. L. (2016). Hubungan tingkat depresi dan kualitas hidup pada pasien gagal jantung kronik di Poliklinik Jantung RSUP Prof. Dr. RD Kandou Manado. e-CliniC, 4(1).
Townsend, M. (2002). Systematic Review of clinical trials examining the effects of religion on health. Southern Medical Journal,95(12), 1429-1434. doi:10.1097/00007611-200212000-00015
Uchmanowicz, I., & Gobbens, R. J. (2015). The relationship between frailty, anxiety and depression, and health-related quality of life in elderly patients with heart failure. Clinical Interventions in Aging, 10, 1595-1600. doi:10.2147/cia.s90077
Wang, J., Sereika, S. M., Styn, M. A., & Burke, L. E. (2013). Factors associated with health-related quality of life among overweight or obese adults. Journal of Clinical Nursing,22(15-16), 2172-2182. doi:10.1111/jocn.12280
Waters, H., Saadah, F., & Pradhan, M. (2003). The impact of the 1997-98 East Asian economic crisis on health and health care in Indonesia. Health Policy and Planning,18(2), 172-181. doi:10.1093/heapol/czg022
Westlake, C., Dracup, K., Creaser, J., Livingston, N., Heywood, J., Huiskes, B. L., . . . Hamilton, M. (2002). Correlates of health-related quality of life in patients with heart failure. Heart & Lung: The Journal of Acute and Critical Care,31(2), 85-93. doi:10.1067/mhl.2002.122839
WHO, E. C. (2004). Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet (London, England), 363(9403), 157.
Wilson, J., & McMillan, S. (2013). Symptoms experienced by heart failure patients in hospice care. Journal of Hospice & Palliative Nursing,15(1), 22-23. doi:10.1097/njh.0b013e3182803351
Wong, C. Y., Chaudhry, S. I., Desai, M. M., & Krumholz, H. M. (2011). Trends in comorbidity, disability, and polypharmacy in heart failure. The American Journal of Medicine,124(2), 136-143. doi:10.1016/j.amjmed.2010.08.017
World Health Organization (1996). Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychological Medicine, 28(3), 551-558. doi:10.1017/s0033291798006667
World Health Organization. (1996). WHOQOL-BREF: Introduction, administration, scoring and generic version of the assessment: Field trial version, December 1996.
Xu, J., Nolan, M. T., Heinze, K., Yenokyan, G., Hughes, M. T., Johnson, J., . . . Lee, M. C. (2015). Symptom frequency, severity, and quality of life among persons with three disease trajectories: Cancer, ALS, and CHF. Applied Nursing Research,28(4), 311-315. doi:10.1016/j.apnr.2015.03.005
Yancy, C., Jessup, M., Bozkurt, B., Butler, J., Casey, D., Drazner, M., . . . Wilkoff, B. (2013). 2013 ACCF/AHA guideline for the management of heart failure: A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation, 128(16), e240-e327.
Yu, D. S., Lee, D. T., & Woo, J. (2010). Improving health-related quality of life of patients with chronic heart failure: Effects of relaxation therapy. Journal of Advanced Nursing,66(2), 392-403. doi:10.1111/j.1365-2648.2009.05198.x
Zambroski, C. H., Moser, D. K., Bhat, G., & Ziegler, C. (2005). Impact of symptom prevalence and symptom burden on quality of life in patients with heart failure. European Journal of Cardiovascular Nursing,4(3), 198-206. doi:10.1016/j.ejcnurse.2005.03.010
Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., & Cleland, J. G. (2016). Exploring quality of life in patients with and without heart failure. International Journal of Cardiology,202, 676-684. doi:10.1016/j.ijcard.2015.09.076
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