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系統識別號 U0026-0408201115445600
論文名稱(中文) 後十字韌帶缺損與接受重建術患者之下肢運動學與動力學分析
論文名稱(英文) Lower-Limb Kinematic and Kinetic Analysis for Individuals with Deficient- and Reconstructed-Posterior Cruciate Ligament
校院名稱 成功大學
系所名稱(中) 醫學工程研究所碩博士班
系所名稱(英) Institute of Biomedical Engineering
學年度 99
學期 2
出版年 100
研究生(中文) 劉玫舫
研究生(英文) Mei-Fang Liu
電子信箱 mefali@kmu.edu.tw
學號 p8891108
學位類別 博士
語文別 英文
論文頁數 109頁
口試委員 指導教授-蘇芳慶
口試委員-張志涵
口試委員-陳天送
口試委員-林昭宏
口試委員-陳文玲
口試委員-周伯禧
召集委員-林光華
中文關鍵字 後十字韌帶缺損  後十字韌帶重建  膝關節  運動學  動力學 
英文關鍵字 PCL deficiency  PCL reconstruction  knee joint  kinematics  kinetics 
學科別分類
中文摘要 後十字韌帶受傷後的臨床表現有很大的差異性,尤其是單獨後十字韌帶斷裂的患者,部分患者接受保守治療即有不錯的功能恢復,但仍有部分患者持續存在著膝關節疼痛與不穩定的症狀,無法恢復受傷前的活動程度,最後仍須選擇接受手術重建。單獨後十字韌帶受傷患者在進行日常的功能活動是否會造成下肢動作型態或關節負荷的異常,如果接受手術重建後,下肢關節的運動學與動力學是否可恢復至與健康未受傷者相同,相關的研究非常有限。為了增進對單獨後十字韌帶受傷後臨床表現的瞭解,提供臨床預後評估與治療策略決定的參考,因此對這群患者進行完整的下肢運動學與動力學分析有其必要性。
本研究的研究對象包含慢性單獨後十字韌帶缺損與接受後十字韌帶重建術後超過一年的患者,根據患者主觀描述再將慢性單獨後十字韌帶缺損患者分為有症狀與無症狀兩組,另外,控制組則是下肢未曾有嚴重肌肉骨骼傷害的健康成年人,每組分別有十名受試者。透過三度空間動作分析系統與力板,分析起立坐下、蹲下與平地行走三項日常動作的下肢關節運動學與動力學。研究目的如下: (1)建立後十字韌帶受傷患者(包括有症狀與無症狀後十字韌帶缺損與後十字韌帶重建術後的患者)從事三項日常活動的下肢生物力學特徵,探討與健康未受傷者之間的差異。(2) 比較患側與健側的各項生物力學參數,探討後十字韌帶受傷患者在動作對稱性的表現。(3) 從受傷後時間、韌帶鬆弛度、與活動程度與動作適應策略各方面,探討可能影響後十字韌帶受傷預後的因素。研究結果歸納如下:(1) 有症狀後十字韌帶缺損患者的下肢運動學與動力學與健康未受傷者較接近,兩側不對稱情形也不顯著;無症狀後十字韌帶缺損患者與健康未受傷者在步態站立末期時膝關節爆發力的表現不同,而且兩側不對稱的現象則普遍地存在於三項動作中。 (2) 無論是受傷後時間、韌帶鬆弛度、或活動程度,有症狀與無症狀後十字韌帶缺損受試者之間都沒有顯著差異,顯示這些因素並不是影響其預後的直接因素,兩組受試者的下肢神經肌肉調適的能力,可能才是影響受傷後預後的主要原因。 (3) 接受單束後十字韌帶重建術後,雖然有可接受的功能回復,但在下肢運動學與動力學方面,從事蹲下與行走時仍存在著與健康未受傷者的差異,而從事站立坐下時也有明顯的兩側不對稱。
本研究提供了一個關於單獨後十字韌帶受傷後從事功能活動的下肢運動學與動力學研究的開端,將患者做適當的分類後,發現患者有不同的適應策略,可能是影響受傷後預後的重要因素。我們也針對接受手術重建的受試者進行了相同的生物力學分析,提供後續的研究一些可行的方向。
英文摘要 Clinical studies of posterior cruciate ligament (PCL) injuries have yielded disparate results. This is especially true for patients with isolated PCL tears as some of these patients recovered reasonably with conservative treatment; others, however, continued to suffer from knee joint pain and instability and were unable to return to their level of activity prior to the injury and thus had to resort to surgical reconstruction. There is a dearth of studies on abnormalities of movement patterns or joint loads in the lower limb of patients suffering from isolated PCL injuries in activities of daily living and whether patients who undergo surgical reconstruction can return to the level of joint kinematics and kinetics they had prior to their injuries. It is necessary to conduct a comprehensive analysis of the kinematics and kinetics of the lower limbs of these patients to gain a better understanding of the clinical performance of patients with isolated PCL injuries, to serve as reference for evaluating the clinical prognosis and establishing treatment strategies.
The participants in this study were patients with chronic isolated PCL injuries and patients who underwent PCL reconstructive surgery more than a year ago. The patients are classified as symptomatic and asymptomatic based on their subjective descriptions of their PCL injuries. The control group, on the other hand, comprises healthy adults that have never suffered from severe musculoskeletal injuries in their lower limbs. Each group comprises 10 participants. This study analyzes the lower limb joint kinematics and kinetics of three tasks – sit-stand-sit, squat, and level walk – using a three-dimensional motion analysis system and two force plates. The aims of this study are as follows. (1) To identify the lower limb biomechanics of patients with PCL injuries (including patients with symptomatic and asymptomatic PCL injuries and patients who underwent PCL reconstructive surgery) when conducting three tasks to identify differences with healthy adults. (2) To compare the biomechanical parameters of the involved and noninvolved sides to determine the motion asymmetry of patients with PCL injuries. (3) To observe factors such as time since injury, ligament laxity, activity level, and movement adaptation strategies following injury to identify possible factors that could influence the prognosis of PCL injuries. The results of this study are as follows. (1) The lower limb kinematics and kinetics of patients with symptomatic PCL injuries had roughly the same performance as the healthy adults did and the asymmetry was not significant. Conversely, the knee joint power at the terminal stance of the gait of patients with asymptomatic PCL injuries was different from those of healthy adults and the asymmetry was evident in all three tasks. (2) There were no significant differences between patients with symptomatic and asymptomatic PCL injuries in terms of time since injury, ligament laxity, and activity level, indicating that these were not key factors that directly influence prognosis. The lower limb neuromuscular adaptive capacity of the two groups might be the key factor that influences prognosis after injury. (3) Single-bundle PCL reconstructive surgery was able to repair some functions, but it was evident that the lower limb kinematics and kinetics of patients were different from that of healthy adults when doing squats and level walks; the patients were also evidently asymmetric when doing sit-stand-sit.
This study pioneers research on the lower limb kinematics and kinetics of patients with isolated PCL injuries. This study divided participants into groups and discovered that patients employed various adaptation strategies, which could be a key factor influencing the prognosis after injury. This study also conducted the same biomechanical analyses on patients who underwent surgical reconstruction to provide a feasible direction for future research.
論文目次 CHAPTER 1 INTRODUCTION 1
1.1 Research Background 1
1.2 Overview of the Posterior Cruciate Ligament Injury 2
1.2.1 Anatomy and Function of the Posterior Cruciate Ligament 2
1.2.2 Mechanism of Injury 3
1.2.3 Incidence of Injury 3
1.2.4 Classification and Treatment Strategy 4
1.2.5 Natural History of Nonoperatively Treated Isolated PCL Injuries 6
1.2.6 PCL Reconstruction: Techniques and Clinical Outcomes 9
1.3 Purposes of This Study 11
1.4 Hypotheses 13
CHAPTER 2 LITERATURE REVIEW 14
2.1 Biomechanical Properties of the PCL 14
2.1.1 PCL Forces during Different Conditions 14
2.1.2 Three-Dimensional Deformations of the PCL 17
2.2 Biomechanics of PCL Deficiency 17
2.2.1 Effect of Cutting PCL on the Knee Laxity- In Vitro Studies 17
2.2.2 In Vivo Kinematics and Kinetics of PCL Deficiency 20
2.3 Biomechanics of PCL Reconstruction 24
2.3.1 Effect of PCL Reconstruction on Restoration of the Knee Stability and Kinematics- In Vitro Studies 24
2.3.2 In Vivo Kinematics and Kinetics of PCL Reconstruction 26
CHAPTER 3 RESEARCH DESIGN AND METHODS 28
3.1 Subjects 28
3.1.1 Subjects with Chronic Isolated PCL Deficiency 28
3.1.2 Subjects with PCL Reconstruction 29
3.1.3 Normal Controls 29
3.2 Instrumentation 32
3.3 Procedure 32
3.4 Data Processing 34
3.4.1 Spatiotemporal Variables 37
3.4.2 Kinematic Variables 38
3.4.3 Kinetic Variables 38
3.5 Statistical Analysis 39
CHAPTER 4 RESULTS 40
4.1 Performance Consistency 40
4.2 Between-Group Comparisons 41
4.2.1 Walk Tasks 41
4.2.2 Sit-Stand-Sit Tasks 48
4.2.3 Squat Tasks 54
4.3 Symmetry: Between-Limb Comparisons 60
4.3.1 Symptomatic PCLD group 60
4.3.2 Asymptomatic PCLD group 64
4.3.3 PCLR group 73
CHAPTER 5 DISCUSSION 81
5.1 Selection and Categorization of Subjects 81
5.2 The Biomechanical Characteristics and Influencing Factors of the Three Tasks 82
5.2.1 Walk Tasks 82
5.2.2 Sit-Stand-Sit Tasks 83
5.2.3 Squat Tasks 85
5.3 Movement Adaptation Strategies Adopted after PCL Injuries 87
5.3.1 PCLD Groups 88
5.3.2 PCLR Group 92
5.4 Limitations of This Study 94
5.5 Future Directions 95
CHAPTER 6 CONCLUSIONS 96

References 98
Appendices 106
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